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rDNA magnification is a unique feature of germline stem cells

Ribosomal DNA (rDNA) encodes ribosomal RNA and exists as tandem repeats of hundreds of copies in the eukaryotic genome to meet the high demand of ribosome biogenesis. Tandemly repeated DNA elements are inherently unstable; thus, mechanisms must exist to maintain rDNA copy number (CN), in particular...

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Detalles Bibliográficos
Autores principales:	Nelson, Jonathan O., Kumon, Tomohiro, Yamashita, Yukiko M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666004/ https://www.ncbi.nlm.nih.gov/pubmed/37967216 http://dx.doi.org/10.1073/pnas.2314440120

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