Cellular nucleic acid-binding protein restricts SARS-CoV-2 by regulating interferon and disrupting RNA–protein condensates

A detailed understanding of the innate immune mechanisms involved in restricting SARS-CoV-2 infection and how the virus disrupts these processes could reveal new strategies to boost antiviral mechanisms and develop therapeutics for COVID-19. Here, we identify cellular nucleic acid-binding protein (C...

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Detalles Bibliográficos
Autores principales: Chen, Yongzhi, Lei, Xuqiu, Jiang, Zhaozhao, Humphries, Fiachra, Parsi, Krishna Mohan, Mustone, Nicholas J., Ramos, Irene, Mutetwa, Tinaye, Fernandez-Sesma, Ana, Maehr, René, Caffrey, Daniel R., Fitzgerald, Katherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666094/
https://www.ncbi.nlm.nih.gov/pubmed/37963251
http://dx.doi.org/10.1073/pnas.2308355120

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