Assessment of Novel Mesothelin-Specific Human Antibody Domain VH-Fc Fusion Proteins-Based PET Agents

[Image: see text] Mesothelin (MSLN) is a tumor-associated antigen found in a variety of cancers and is a target for imaging and therapeutic applications in MSLN-expressing tumors. We have developed high affinity anti-MSLN human VH domain antibodies, providing alternative targeting vectors to convent...

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Detalles Bibliográficos
Autores principales: Sun, Zehua, Jaswal, Ambika P., Chu, Xiaojie, Rajkumar, Harikrishnan, Cortez, Angel G., Edinger, Robert, Rose, Max, Josefsson, Anders, Bhise, Abhinav, Huang, Ziyu, Ishima, Rieko, Mellors, John W, Dimitrov, Dimiter S., Li, Wei, Nedrow, Jessie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666227/
https://www.ncbi.nlm.nih.gov/pubmed/38027361
http://dx.doi.org/10.1021/acsomega.3c04492

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