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Effect of 10.6-μm CO(2) laser moxibustion on the fastest 15-m walking time in patients with knee osteoarthritis: a double-blind, sham-controlled, multi-site randomized trial

BACKGROUND: In this study, we investigated the impact of 10.6-μm CO(2) laser moxibustion (LM) on the fastest 15-m walking time in individuals suffering from knee osteoarthritis (KOA). METHODS: A total of 392 individuals diagnosed with KOA and meeting the specified eligibility criteria were assigned...

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Autores principales: Chen, Lusheng, Zhao, Ling, Cheng, Ke, Lin, Lin, Wu, Fan, Shen, Xueyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666435/
https://www.ncbi.nlm.nih.gov/pubmed/37993959
http://dx.doi.org/10.1186/s13018-023-04380-6
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author Chen, Lusheng
Zhao, Ling
Cheng, Ke
Lin, Lin
Wu, Fan
Shen, Xueyong
author_facet Chen, Lusheng
Zhao, Ling
Cheng, Ke
Lin, Lin
Wu, Fan
Shen, Xueyong
author_sort Chen, Lusheng
collection PubMed
description BACKGROUND: In this study, we investigated the impact of 10.6-μm CO(2) laser moxibustion (LM) on the fastest 15-m walking time in individuals suffering from knee osteoarthritis (KOA). METHODS: A total of 392 individuals diagnosed with KOA and meeting the specified eligibility criteria were assigned randomly into two groups: the LM treatment group and the sham LM control group (ratio 1:1). Both groups received either LM therapy or simulated LM therapy to address the affected area of the knee joint. This treatment was administered three times a week for a duration of 4 weeks. RESULTS: In the LM group, the fastest 15-m walking times at both Week 4 and Week 12 were significantly reduced compared to the times before treatment (all P < 0.05). However, in the sham LM group, there were no notable differences in the fastest 15-m walking times after treatment (all P > 0.05). Moreover, the LM group exhibited shorter 15-m walking times than the sham LM group at both Week 4 and Week 12 (all P < 0.05). CONCLUSION: The use of CO(2) LM can lead to a substantial enhancement in the fastest 15-m walking time of individuals suffering from KOA, and its therapeutic impact can last for a minimum of 8 weeks post-treatment. The fastest 15-m walking time serves as an indicator of alterations in the walking capacity of patients with KOA.
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spelling pubmed-106664352023-11-22 Effect of 10.6-μm CO(2) laser moxibustion on the fastest 15-m walking time in patients with knee osteoarthritis: a double-blind, sham-controlled, multi-site randomized trial Chen, Lusheng Zhao, Ling Cheng, Ke Lin, Lin Wu, Fan Shen, Xueyong J Orthop Surg Res Research Article BACKGROUND: In this study, we investigated the impact of 10.6-μm CO(2) laser moxibustion (LM) on the fastest 15-m walking time in individuals suffering from knee osteoarthritis (KOA). METHODS: A total of 392 individuals diagnosed with KOA and meeting the specified eligibility criteria were assigned randomly into two groups: the LM treatment group and the sham LM control group (ratio 1:1). Both groups received either LM therapy or simulated LM therapy to address the affected area of the knee joint. This treatment was administered three times a week for a duration of 4 weeks. RESULTS: In the LM group, the fastest 15-m walking times at both Week 4 and Week 12 were significantly reduced compared to the times before treatment (all P < 0.05). However, in the sham LM group, there were no notable differences in the fastest 15-m walking times after treatment (all P > 0.05). Moreover, the LM group exhibited shorter 15-m walking times than the sham LM group at both Week 4 and Week 12 (all P < 0.05). CONCLUSION: The use of CO(2) LM can lead to a substantial enhancement in the fastest 15-m walking time of individuals suffering from KOA, and its therapeutic impact can last for a minimum of 8 weeks post-treatment. The fastest 15-m walking time serves as an indicator of alterations in the walking capacity of patients with KOA. BioMed Central 2023-11-22 /pmc/articles/PMC10666435/ /pubmed/37993959 http://dx.doi.org/10.1186/s13018-023-04380-6 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Chen, Lusheng
Zhao, Ling
Cheng, Ke
Lin, Lin
Wu, Fan
Shen, Xueyong
Effect of 10.6-μm CO(2) laser moxibustion on the fastest 15-m walking time in patients with knee osteoarthritis: a double-blind, sham-controlled, multi-site randomized trial
title Effect of 10.6-μm CO(2) laser moxibustion on the fastest 15-m walking time in patients with knee osteoarthritis: a double-blind, sham-controlled, multi-site randomized trial
title_full Effect of 10.6-μm CO(2) laser moxibustion on the fastest 15-m walking time in patients with knee osteoarthritis: a double-blind, sham-controlled, multi-site randomized trial
title_fullStr Effect of 10.6-μm CO(2) laser moxibustion on the fastest 15-m walking time in patients with knee osteoarthritis: a double-blind, sham-controlled, multi-site randomized trial
title_full_unstemmed Effect of 10.6-μm CO(2) laser moxibustion on the fastest 15-m walking time in patients with knee osteoarthritis: a double-blind, sham-controlled, multi-site randomized trial
title_short Effect of 10.6-μm CO(2) laser moxibustion on the fastest 15-m walking time in patients with knee osteoarthritis: a double-blind, sham-controlled, multi-site randomized trial
title_sort effect of 10.6-μm co(2) laser moxibustion on the fastest 15-m walking time in patients with knee osteoarthritis: a double-blind, sham-controlled, multi-site randomized trial
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666435/
https://www.ncbi.nlm.nih.gov/pubmed/37993959
http://dx.doi.org/10.1186/s13018-023-04380-6
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