Direct inhibition of dioxygenases TET1 by the rheumatoid arthritis drug auranofin selectively induces cancer cell death in T-ALL

T-cell acute lymphoblastic leukemia (T-ALL) is a type of hematologic tumor with malignant proliferation of hematopoietic progenitor cells. However, traditional clinical treatment of T-ALL included chemotherapy and stem cell transplantation always lead to recurrence and poor prognosis, thus new thera...

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Detalles Bibliográficos
Autores principales: Chen, Long, Ren, Anqi, Zhao, Yuan, Chen, Hangyu, Wu, Qifang, Zheng, Mengzhu, Zhang, Zijian, Zhang, Tongcun, Zhong, Wu, Lin, Jian, Zhu, Haichuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666452/
https://www.ncbi.nlm.nih.gov/pubmed/37993905
http://dx.doi.org/10.1186/s13045-023-01513-6

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