Trichinella spiralis cathepsin L induces macrophage M1 polarization via the NF-κB pathway and enhances the ADCC killing of newborn larvae

BACKGROUND: During the early stages of Trichinella spiralis infection, macrophages predominantly undergo polarization to the M1-like phenotype, causing the host’s inflammatory response and resistance against T. spiralis infection. As the disease progresses, the number of M2-type macrophages graduall...

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Detalles Bibliográficos
Autores principales: Liu, Ruo Dan, Meng, Xiang Yu, Le Li, Chen, Xu, Qiu Yi, Lin, Xin Zhi, Dong, Bo Rang, Ye, Chu Yan, Miao, Tian Tian, Si, Xin Yi, Long, Shao Rong, Cui, Jing, Wang, Zhong Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666456/
https://www.ncbi.nlm.nih.gov/pubmed/37993938
http://dx.doi.org/10.1186/s13071-023-06051-1

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