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Educational disparities in Brazil may interfere with the cognitive performance of Parkinson's disease patients

The prevalence of cognitive impairment in Parkinson's disease (PD) is about 20% to 60%. The Mini-Mental Status Examination (MMSE) is the most used cognitive screening test. OBJECTIVE: To evaluate the influence of clinical and demographic characteristics, specifically the education level, on the...

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Autores principales: Lima, Danielle Pessoa, Bonfadini, Janine de Carvalho, Carneiro, Alexandre Henrique Silva, de Almeida, Samuel Brito, Viana, Antonio Brazil, Nogueira e Silva, Ana Cecília, Roriz, Jarbas de Sá, Braga, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666553/
https://www.ncbi.nlm.nih.gov/pubmed/38028380
http://dx.doi.org/10.1590/1980-5764-DN-2022-0084
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author Lima, Danielle Pessoa
Bonfadini, Janine de Carvalho
Carneiro, Alexandre Henrique Silva
de Almeida, Samuel Brito
Viana, Antonio Brazil
Nogueira e Silva, Ana Cecília
Roriz, Jarbas de Sá
Braga, Pedro
author_facet Lima, Danielle Pessoa
Bonfadini, Janine de Carvalho
Carneiro, Alexandre Henrique Silva
de Almeida, Samuel Brito
Viana, Antonio Brazil
Nogueira e Silva, Ana Cecília
Roriz, Jarbas de Sá
Braga, Pedro
author_sort Lima, Danielle Pessoa
collection PubMed
description The prevalence of cognitive impairment in Parkinson's disease (PD) is about 20% to 60%. The Mini-Mental Status Examination (MMSE) is the most used cognitive screening test. OBJECTIVE: To evaluate the influence of clinical and demographic characteristics, specifically the education level, on the MMSE score in PD patients of a northeast Brazilian sample. METHODS: We performed a cross-sectional study of 198 PD patients at a Movement Disorders outpatient clinic in Fortaleza, CE, Brazil. Participants were assessed by detailed clinical history, modified Hoehn and Yahr staging (HY), geriatric depression scale (GDS) and MMSE. RESULTS: We found that 68% of patients had MMSE scores below the Brazilian thresholds, which were based in Brucki et al. study (2003). There was a statistically significant difference in the bivariate analysis between educational level and cut-off classification for MMSE. More years of formal schooling were associated with more patients scoring below threshold. We found that 75%, 68.8%, and 79.7% of individuals with more than 11, 9 to 11, and 4 to 8 years of formal schooling, respectively, were below the suggested Brazilian Brucki's threshold. GDS and age were negatively correlated with total MMSE and all its domains. There was no correlation between disease duration and MMSE. Subjects with hallucinations had lower scores. CONCLUSION: Most of the sample had lower performance according to Brazilian thresholds, but there was no control group and no neuropsychological test in this study. Further studies in northeast Brazil are needed to review MMSE cut-off values.
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spelling pubmed-106665532023-11-20 Educational disparities in Brazil may interfere with the cognitive performance of Parkinson's disease patients Lima, Danielle Pessoa Bonfadini, Janine de Carvalho Carneiro, Alexandre Henrique Silva de Almeida, Samuel Brito Viana, Antonio Brazil Nogueira e Silva, Ana Cecília Roriz, Jarbas de Sá Braga, Pedro Dement Neuropsychol Original Article The prevalence of cognitive impairment in Parkinson's disease (PD) is about 20% to 60%. The Mini-Mental Status Examination (MMSE) is the most used cognitive screening test. OBJECTIVE: To evaluate the influence of clinical and demographic characteristics, specifically the education level, on the MMSE score in PD patients of a northeast Brazilian sample. METHODS: We performed a cross-sectional study of 198 PD patients at a Movement Disorders outpatient clinic in Fortaleza, CE, Brazil. Participants were assessed by detailed clinical history, modified Hoehn and Yahr staging (HY), geriatric depression scale (GDS) and MMSE. RESULTS: We found that 68% of patients had MMSE scores below the Brazilian thresholds, which were based in Brucki et al. study (2003). There was a statistically significant difference in the bivariate analysis between educational level and cut-off classification for MMSE. More years of formal schooling were associated with more patients scoring below threshold. We found that 75%, 68.8%, and 79.7% of individuals with more than 11, 9 to 11, and 4 to 8 years of formal schooling, respectively, were below the suggested Brazilian Brucki's threshold. GDS and age were negatively correlated with total MMSE and all its domains. There was no correlation between disease duration and MMSE. Subjects with hallucinations had lower scores. CONCLUSION: Most of the sample had lower performance according to Brazilian thresholds, but there was no control group and no neuropsychological test in this study. Further studies in northeast Brazil are needed to review MMSE cut-off values. Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento 2023-11-20 /pmc/articles/PMC10666553/ /pubmed/38028380 http://dx.doi.org/10.1590/1980-5764-DN-2022-0084 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Original Article
Lima, Danielle Pessoa
Bonfadini, Janine de Carvalho
Carneiro, Alexandre Henrique Silva
de Almeida, Samuel Brito
Viana, Antonio Brazil
Nogueira e Silva, Ana Cecília
Roriz, Jarbas de Sá
Braga, Pedro
Educational disparities in Brazil may interfere with the cognitive performance of Parkinson's disease patients
title Educational disparities in Brazil may interfere with the cognitive performance of Parkinson's disease patients
title_full Educational disparities in Brazil may interfere with the cognitive performance of Parkinson's disease patients
title_fullStr Educational disparities in Brazil may interfere with the cognitive performance of Parkinson's disease patients
title_full_unstemmed Educational disparities in Brazil may interfere with the cognitive performance of Parkinson's disease patients
title_short Educational disparities in Brazil may interfere with the cognitive performance of Parkinson's disease patients
title_sort educational disparities in brazil may interfere with the cognitive performance of parkinson's disease patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666553/
https://www.ncbi.nlm.nih.gov/pubmed/38028380
http://dx.doi.org/10.1590/1980-5764-DN-2022-0084
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