Formulation of Glibenclamide proniosomes for oral administration: Pharmaceutical and pharmacodynamics evaluation

Glibenclamide (GB), oral antidiabetic sulfonylurea, is used in the management of diabetes mellitus type II. It suffers from low bioavailability due to low water solubility. This work aimed to enhance the dissolution of GB by formulating the drug as a proniosomes which then improves the pharmacologic...

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Detalles Bibliográficos
Autores principales: Alshora, Doaa, Ibrahim, Mohamed, Alanazi, Nouf, Alowyid, Malak, Ali Alnakhli, Zainab, Mohammed Alshiban, Noura, Maodaa, Saleh, Alyami, Nouf M., Alotaibi, Ibrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666557/
https://www.ncbi.nlm.nih.gov/pubmed/38028219
http://dx.doi.org/10.1016/j.jsps.2023.101830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666557/
https://www.ncbi.nlm.nih.gov/pubmed/38028219
http://dx.doi.org/10.1016/j.jsps.2023.101830

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