Cargando…

A classifier model for prostate cancer diagnosis using CNNs and transfer learning with multi-parametric MRI

Prostate cancer (PCa) is a major global concern, particularly for men, emphasizing the urgency of early detection to reduce mortality. As the second leading cause of cancer-related male deaths worldwide, precise and efficient diagnostic methods are crucial. Due to high and multiresolution MRI in PCa...

Descripción completa

Detalles Bibliográficos
Autores principales: Mehmood, Mubashar, Abbasi, Sadam Hussain, Aurangzeb, Khursheed, Majeed, Muhammad Faran, Anwar, Muhammad Shahid, Alhussein, Musaed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666634/
https://www.ncbi.nlm.nih.gov/pubmed/38023149
http://dx.doi.org/10.3389/fonc.2023.1225490
_version_ 1785139086850260992
author Mehmood, Mubashar
Abbasi, Sadam Hussain
Aurangzeb, Khursheed
Majeed, Muhammad Faran
Anwar, Muhammad Shahid
Alhussein, Musaed
author_facet Mehmood, Mubashar
Abbasi, Sadam Hussain
Aurangzeb, Khursheed
Majeed, Muhammad Faran
Anwar, Muhammad Shahid
Alhussein, Musaed
author_sort Mehmood, Mubashar
collection PubMed
description Prostate cancer (PCa) is a major global concern, particularly for men, emphasizing the urgency of early detection to reduce mortality. As the second leading cause of cancer-related male deaths worldwide, precise and efficient diagnostic methods are crucial. Due to high and multiresolution MRI in PCa, computer-aided diagnostic (CAD) methods have emerged to assist radiologists in identifying anomalies. However, the rapid advancement of medical technology has led to the adoption of deep learning methods. These techniques enhance diagnostic efficiency, reduce observer variability, and consistently outperform traditional approaches. Resource constraints that can distinguish whether a cancer is aggressive or not is a significant problem in PCa treatment. This study aims to identify PCa using MRI images by combining deep learning and transfer learning (TL). Researchers have explored numerous CNN-based Deep Learning methods for classifying MRI images related to PCa. In this study, we have developed an approach for the classification of PCa using transfer learning on a limited number of images to achieve high performance and help radiologists instantly identify PCa. The proposed methodology adopts the EfficientNet architecture, pre-trained on the ImageNet dataset, and incorporates three branches for feature extraction from different MRI sequences. The extracted features are then combined, significantly enhancing the model’s ability to distinguish MRI images accurately. Our model demonstrated remarkable results in classifying prostate cancer, achieving an accuracy rate of 88.89%. Furthermore, comparative results indicate that our approach achieve higher accuracy than both traditional hand-crafted feature techniques and existing deep learning techniques in PCa classification. The proposed methodology can learn more distinctive features in prostate images and correctly identify cancer.
format Online
Article
Text
id pubmed-10666634
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-106666342023-01-01 A classifier model for prostate cancer diagnosis using CNNs and transfer learning with multi-parametric MRI Mehmood, Mubashar Abbasi, Sadam Hussain Aurangzeb, Khursheed Majeed, Muhammad Faran Anwar, Muhammad Shahid Alhussein, Musaed Front Oncol Oncology Prostate cancer (PCa) is a major global concern, particularly for men, emphasizing the urgency of early detection to reduce mortality. As the second leading cause of cancer-related male deaths worldwide, precise and efficient diagnostic methods are crucial. Due to high and multiresolution MRI in PCa, computer-aided diagnostic (CAD) methods have emerged to assist radiologists in identifying anomalies. However, the rapid advancement of medical technology has led to the adoption of deep learning methods. These techniques enhance diagnostic efficiency, reduce observer variability, and consistently outperform traditional approaches. Resource constraints that can distinguish whether a cancer is aggressive or not is a significant problem in PCa treatment. This study aims to identify PCa using MRI images by combining deep learning and transfer learning (TL). Researchers have explored numerous CNN-based Deep Learning methods for classifying MRI images related to PCa. In this study, we have developed an approach for the classification of PCa using transfer learning on a limited number of images to achieve high performance and help radiologists instantly identify PCa. The proposed methodology adopts the EfficientNet architecture, pre-trained on the ImageNet dataset, and incorporates three branches for feature extraction from different MRI sequences. The extracted features are then combined, significantly enhancing the model’s ability to distinguish MRI images accurately. Our model demonstrated remarkable results in classifying prostate cancer, achieving an accuracy rate of 88.89%. Furthermore, comparative results indicate that our approach achieve higher accuracy than both traditional hand-crafted feature techniques and existing deep learning techniques in PCa classification. The proposed methodology can learn more distinctive features in prostate images and correctly identify cancer. Frontiers Media S.A. 2023-11-09 /pmc/articles/PMC10666634/ /pubmed/38023149 http://dx.doi.org/10.3389/fonc.2023.1225490 Text en Copyright © 2023 Mehmood, Abbasi, Aurangzeb, Majeed, Anwar and Alhussein https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Mehmood, Mubashar
Abbasi, Sadam Hussain
Aurangzeb, Khursheed
Majeed, Muhammad Faran
Anwar, Muhammad Shahid
Alhussein, Musaed
A classifier model for prostate cancer diagnosis using CNNs and transfer learning with multi-parametric MRI
title A classifier model for prostate cancer diagnosis using CNNs and transfer learning with multi-parametric MRI
title_full A classifier model for prostate cancer diagnosis using CNNs and transfer learning with multi-parametric MRI
title_fullStr A classifier model for prostate cancer diagnosis using CNNs and transfer learning with multi-parametric MRI
title_full_unstemmed A classifier model for prostate cancer diagnosis using CNNs and transfer learning with multi-parametric MRI
title_short A classifier model for prostate cancer diagnosis using CNNs and transfer learning with multi-parametric MRI
title_sort classifier model for prostate cancer diagnosis using cnns and transfer learning with multi-parametric mri
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666634/
https://www.ncbi.nlm.nih.gov/pubmed/38023149
http://dx.doi.org/10.3389/fonc.2023.1225490
work_keys_str_mv AT mehmoodmubashar aclassifiermodelforprostatecancerdiagnosisusingcnnsandtransferlearningwithmultiparametricmri
AT abbasisadamhussain aclassifiermodelforprostatecancerdiagnosisusingcnnsandtransferlearningwithmultiparametricmri
AT aurangzebkhursheed aclassifiermodelforprostatecancerdiagnosisusingcnnsandtransferlearningwithmultiparametricmri
AT majeedmuhammadfaran aclassifiermodelforprostatecancerdiagnosisusingcnnsandtransferlearningwithmultiparametricmri
AT anwarmuhammadshahid aclassifiermodelforprostatecancerdiagnosisusingcnnsandtransferlearningwithmultiparametricmri
AT alhusseinmusaed aclassifiermodelforprostatecancerdiagnosisusingcnnsandtransferlearningwithmultiparametricmri
AT mehmoodmubashar classifiermodelforprostatecancerdiagnosisusingcnnsandtransferlearningwithmultiparametricmri
AT abbasisadamhussain classifiermodelforprostatecancerdiagnosisusingcnnsandtransferlearningwithmultiparametricmri
AT aurangzebkhursheed classifiermodelforprostatecancerdiagnosisusingcnnsandtransferlearningwithmultiparametricmri
AT majeedmuhammadfaran classifiermodelforprostatecancerdiagnosisusingcnnsandtransferlearningwithmultiparametricmri
AT anwarmuhammadshahid classifiermodelforprostatecancerdiagnosisusingcnnsandtransferlearningwithmultiparametricmri
AT alhusseinmusaed classifiermodelforprostatecancerdiagnosisusingcnnsandtransferlearningwithmultiparametricmri