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Exosomes from miR-23 Overexpressing Stromal Cells Suppress M1 Macrophage and Inhibit Calcium Oxalate Deposition in Hyperoxaluria Rat Model

PURPOSE: To investigate whether ADSC-derived miR-23-enriched exosomes could protect against calcium oxalate stone formation in a hyperoxaluria rat model. METHODS: An ethylene glycol- (EG-) induced hyperoxaluria rat model and an in vitro model of COM-induced HK-2 cells coculturing with RAW264.7 cells...

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Detalles Bibliográficos
Autores principales:	Yifan, Zhang, Shengli, Zhang, Min, Wang, Wenjie, Cheng, Yi, Sun, Luwei, Xu, Ruipeng, Jia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667050/ https://www.ncbi.nlm.nih.gov/pubmed/38027040 http://dx.doi.org/10.1155/2023/2883623

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