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Generation of evidence-based carboplatin dosing guidelines for neonates and infants

BACKGROUND: To optimally dose childhood cancer patients it is essential that we apply evidence-based dosing approaches. Carboplatin is commonly dosed to achieve a cumulative target exposure (AUC) in children, with target AUC values of 5.2–7.8 mg/ml.min defined. To achieve these exposures patients ar...

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Detalles Bibliográficos
Autores principales: Barnett, Shelby, Makin, Guy, Tweddle, Deborah A., Osborne, Caroline, Veal, Gareth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667364/
https://www.ncbi.nlm.nih.gov/pubmed/37816842
http://dx.doi.org/10.1038/s41416-023-02456-y

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