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Trifluoromethylated hydrazones and acylhydrazones as potent nitrogen-containing fluorinated building blocks
Nitrogen-containing organofluorine derivatives, which are prepared using fluorinated building blocks, are among the most important active fragments in various pharmaceutical and agrochemical products. This review focuses on the reactivity, synthesis, and applications of fluoromethylated hydrazones a...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Beilstein-Institut
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667715/ https://www.ncbi.nlm.nih.gov/pubmed/38025086 http://dx.doi.org/10.3762/bjoc.19.127 |
Sumario: | Nitrogen-containing organofluorine derivatives, which are prepared using fluorinated building blocks, are among the most important active fragments in various pharmaceutical and agrochemical products. This review focuses on the reactivity, synthesis, and applications of fluoromethylated hydrazones and acylhydrazones. It summarizes recent methodologies that have been used for the synthesis of various nitrogen-containing organofluorine compounds. |
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