cGAS‐STING Pathway Activation and Systemic Anti‐Tumor Immunity Induction via Photodynamic Nanoparticles with Potent Toxic Platinum DNA Intercalator Against Uveal Melanoma

The cGAS‐STING pathway, as a vital innate immune signaling pathway, has attracted considerable attention in tumor immunotherapy research. However, STING agonists are generally incapable of targeting tumors, thus limiting their clinical applications. Here, a photodynamic polymer (P1) is designed to e...

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Detalles Bibliográficos
Autores principales: Tao, Hui, Tan, Jia, Zhang, Hanchen, Ren, Hong, Cai, Ziyi, Liu, Hanhan, Wen, Bingyu, Du, Jiaqi, Li, Gaoyang, Chen, Shijie, Xiao, Haihua, Deng, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667795/
https://www.ncbi.nlm.nih.gov/pubmed/37807827
http://dx.doi.org/10.1002/advs.202302895

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