Cargando…

Rapidly progressing severe coagulopathy and thrombocytopenia in extreme anorexia nervosa patient with small bowel strangulation: A case report

INTRODUCTION: Anorexia nervosa (AN) is characterized by severe dietary restriction or other weight loss behaviors motivated by a strong fear of body weight gain and a disturbed body image. In this paper, we report a case of an extreme AN patient, in whom severe coagulopathy and thrombocytopenia rapi...

Descripción completa

Detalles Bibliográficos
Autores principales: Miyachi, Yosuke, Sakiko, Kondo, Yokoi, Tadao, Kaido, Toshimi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667876/
https://www.ncbi.nlm.nih.gov/pubmed/37898008
http://dx.doi.org/10.1016/j.ijscr.2023.108985
_version_ 1785139346531155968
author Miyachi, Yosuke
Sakiko, Kondo
Yokoi, Tadao
Kaido, Toshimi
author_facet Miyachi, Yosuke
Sakiko, Kondo
Yokoi, Tadao
Kaido, Toshimi
author_sort Miyachi, Yosuke
collection PubMed
description INTRODUCTION: Anorexia nervosa (AN) is characterized by severe dietary restriction or other weight loss behaviors motivated by a strong fear of body weight gain and a disturbed body image. In this paper, we report a case of an extreme AN patient, in whom severe coagulopathy and thrombocytopenia rapidly progressed with strangulation obstruction. PRESENTATION OF CASE: A female patient in her 20's with previous history of AN came to our hospital complaining acute onset abdominal pain. Her body mass index at presentation was 12.1 kg/m(2); thus, she was classified as an “extreme” AN (BMI <15) according to DSM-5 classification. Abdominal CT scan showed small bowel obstruction without strangulation. Although severe leukopenia appeared soon after admission, platelet count and coagulation tests were maintained relatively well. Due to her severe malnutrition, we proposed nutritional therapy and subsequent surgical adhesiolysis; however, she refused any kind of nutritional therapy. On admission day 13, she suddenly developed a strangulation obstruction. At the same time, severe coagulopathy and thrombocytopenia rapidly progressed. Emergency laparotomy was performed using a massive blood transfusion. Bowel strangulation was successfully released; however, intraabdominal bleeding was repeated postoperatively and three more operations were required until complete hemostasis and abdominal closure. After long rehabilitation, she was discharged from our hospital on day 116. DISCUSSION: The medical comorbidities associated with AN extend various organ systems; among them, the hematologic complication can be a life-threatening problem during emergency surgery for a patient with AN. CONCLUSION: Knowledge about the pathophysiology of AN is quite essential for all surgeons.
format Online
Article
Text
id pubmed-10667876
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-106678762023-10-24 Rapidly progressing severe coagulopathy and thrombocytopenia in extreme anorexia nervosa patient with small bowel strangulation: A case report Miyachi, Yosuke Sakiko, Kondo Yokoi, Tadao Kaido, Toshimi Int J Surg Case Rep Case Report INTRODUCTION: Anorexia nervosa (AN) is characterized by severe dietary restriction or other weight loss behaviors motivated by a strong fear of body weight gain and a disturbed body image. In this paper, we report a case of an extreme AN patient, in whom severe coagulopathy and thrombocytopenia rapidly progressed with strangulation obstruction. PRESENTATION OF CASE: A female patient in her 20's with previous history of AN came to our hospital complaining acute onset abdominal pain. Her body mass index at presentation was 12.1 kg/m(2); thus, she was classified as an “extreme” AN (BMI <15) according to DSM-5 classification. Abdominal CT scan showed small bowel obstruction without strangulation. Although severe leukopenia appeared soon after admission, platelet count and coagulation tests were maintained relatively well. Due to her severe malnutrition, we proposed nutritional therapy and subsequent surgical adhesiolysis; however, she refused any kind of nutritional therapy. On admission day 13, she suddenly developed a strangulation obstruction. At the same time, severe coagulopathy and thrombocytopenia rapidly progressed. Emergency laparotomy was performed using a massive blood transfusion. Bowel strangulation was successfully released; however, intraabdominal bleeding was repeated postoperatively and three more operations were required until complete hemostasis and abdominal closure. After long rehabilitation, she was discharged from our hospital on day 116. DISCUSSION: The medical comorbidities associated with AN extend various organ systems; among them, the hematologic complication can be a life-threatening problem during emergency surgery for a patient with AN. CONCLUSION: Knowledge about the pathophysiology of AN is quite essential for all surgeons. Elsevier 2023-10-24 /pmc/articles/PMC10667876/ /pubmed/37898008 http://dx.doi.org/10.1016/j.ijscr.2023.108985 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Miyachi, Yosuke
Sakiko, Kondo
Yokoi, Tadao
Kaido, Toshimi
Rapidly progressing severe coagulopathy and thrombocytopenia in extreme anorexia nervosa patient with small bowel strangulation: A case report
title Rapidly progressing severe coagulopathy and thrombocytopenia in extreme anorexia nervosa patient with small bowel strangulation: A case report
title_full Rapidly progressing severe coagulopathy and thrombocytopenia in extreme anorexia nervosa patient with small bowel strangulation: A case report
title_fullStr Rapidly progressing severe coagulopathy and thrombocytopenia in extreme anorexia nervosa patient with small bowel strangulation: A case report
title_full_unstemmed Rapidly progressing severe coagulopathy and thrombocytopenia in extreme anorexia nervosa patient with small bowel strangulation: A case report
title_short Rapidly progressing severe coagulopathy and thrombocytopenia in extreme anorexia nervosa patient with small bowel strangulation: A case report
title_sort rapidly progressing severe coagulopathy and thrombocytopenia in extreme anorexia nervosa patient with small bowel strangulation: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667876/
https://www.ncbi.nlm.nih.gov/pubmed/37898008
http://dx.doi.org/10.1016/j.ijscr.2023.108985
work_keys_str_mv AT miyachiyosuke rapidlyprogressingseverecoagulopathyandthrombocytopeniainextremeanorexianervosapatientwithsmallbowelstrangulationacasereport
AT sakikokondo rapidlyprogressingseverecoagulopathyandthrombocytopeniainextremeanorexianervosapatientwithsmallbowelstrangulationacasereport
AT yokoitadao rapidlyprogressingseverecoagulopathyandthrombocytopeniainextremeanorexianervosapatientwithsmallbowelstrangulationacasereport
AT kaidotoshimi rapidlyprogressingseverecoagulopathyandthrombocytopeniainextremeanorexianervosapatientwithsmallbowelstrangulationacasereport