Cargando…
Metformin reduces hepatocarcinogenesis by inducing downregulation of Cyp26a1 and CD8(+) T cells
BACKGROUND: Hepatocellular carcinoma (HCC) is a highly heterogeneous cancer with major challenges in both prevention and therapy. Metformin, adenosine monophosphate‐activated protein kinase (AMPK) activator, has been suggested to reduce the incidence of HCC when used for patients with diabetes in pr...
Autores principales: | , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668005/ https://www.ncbi.nlm.nih.gov/pubmed/37997519 http://dx.doi.org/10.1002/ctm2.1465 |