Metformin reduces hepatocarcinogenesis by inducing downregulation of Cyp26a1 and CD8(+) T cells

BACKGROUND: Hepatocellular carcinoma (HCC) is a highly heterogeneous cancer with major challenges in both prevention and therapy. Metformin, adenosine monophosphate‐activated protein kinase (AMPK) activator, has been suggested to reduce the incidence of HCC when used for patients with diabetes in pr...

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Detalles Bibliográficos
Autores principales: He, Weizhi, Wang, Xicheng, Chen, Miaomiao, Li, Chong, Chen, Wenjian, Pan, Lili, Cui, Yangyang, Yu, Zhao, Wu, Guoxiu, Yang, Yang, Xu, Mingyang, Dong, Zhaoxuan, Ma, Keming, Wang, Jinghan, He, Zhiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668005/
https://www.ncbi.nlm.nih.gov/pubmed/37997519
http://dx.doi.org/10.1002/ctm2.1465

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