Nuclear envelope assembly relies on CHMP-7 in the absence of BAF–LEM-mediated hole closure

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Barrier-to-autointegration factor (BAF) protein is a DNA-binding protein that crosslinks chromatin to allow mitotic nuclear envelope (NE) assembly. The LAP2-emerin-MAN1 (LEM)-domain protein LEMD2 and ESCRT-II/III hybrid protein CHMP7 close NE holes surrounding spindle microtubules (MTs). BAF binds L...

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Detalles Bibliográficos
Autores principales: Barger, Sarah R., Penfield, Lauren, Bahmanyar, Shirin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668030/
https://www.ncbi.nlm.nih.gov/pubmed/37795681
http://dx.doi.org/10.1242/jcs.261385

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