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A randomized, single ascending dose safety, tolerability and pharmacokinetics study of NicaPlant® in aneurysmal subarachnoid hemorrhage patients undergoing clipping

INTRODUCTION: Aneurysmal subarachnoid hemorrhage (aSAH) is associated with high morbidity and mortality. Post-hemorrhagic vasospasm with neurological deterioration is a major concern in this context. NicaPlant®, a modified release formulation of the calcium channel blocker nicardipine, has shown vas...

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Detalles Bibliográficos
Autores principales:	Kerschbaumer, Johannes, Freyschlag, Christian Franz, Petr, Ondra, Adage, Tiziana, Breitenbach J, Joerg, Wessels, Lars, Wolf, Stefan, Hecht, Nils, Gempt, Jens, Wostrack, Maria, Gmeiner, Matthias, Gollwitzer, Maria, Stefanits, Harald, Bendszus M, Martin, Gruber, Andreas, Meyer, Bernhard, Vajkoczy, Peter, Thomé, Claudius
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668089/ https://www.ncbi.nlm.nih.gov/pubmed/38021019 http://dx.doi.org/10.1016/j.bas.2023.102673

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