Modulation of SLFN11 induces changes in DNA Damage response in breast cancer

BACKGROUND: Lack of Schlafen family member 11 (SLFN11) expression has been recently identified as a dominant genomic determinant of response to DNA damaging agents in numerous cancer types. Thus, several strategies aimed at increasing SLFN11 are explored to restore chemosensitivity of refractory can...

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Detalles Bibliográficos
Autores principales: Raynaud, Christophe Michel, Ahmed, Eiman I., Jabeen, Ayesha, Sanchez, Apryl, Sherif, Shimaa, Carneiro-Lobo, Tatiana C., Awad, Amany, Awartani, Dina, Naik, Adviti, Thomas, Remy, Decock, Julie, Zoppoli, Gabriele, Bedongnetti, Davide, Hendrickx, Wouter R. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668346/
https://www.ncbi.nlm.nih.gov/pubmed/38001424
http://dx.doi.org/10.1186/s12935-023-03144-w

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