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Research progress of biomimetic materials in oral medicine

Biomimetic materials are able to mimic the structure and functional properties of native tissues especially natural oral tissues. They have attracted growing attention for their potential to achieve configurable and functional reconstruction in oral medicine. Though tremendous progress has been made...

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Autores principales: Luo, Xinyu, Niu, Jiayue, Su, Guanyu, Zhou, Linxi, Zhang, Xue, Liu, Ying, Wang, Qiang, Sun, Ningning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668381/
https://www.ncbi.nlm.nih.gov/pubmed/37996886
http://dx.doi.org/10.1186/s13036-023-00382-4
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author Luo, Xinyu
Niu, Jiayue
Su, Guanyu
Zhou, Linxi
Zhang, Xue
Liu, Ying
Wang, Qiang
Sun, Ningning
author_facet Luo, Xinyu
Niu, Jiayue
Su, Guanyu
Zhou, Linxi
Zhang, Xue
Liu, Ying
Wang, Qiang
Sun, Ningning
author_sort Luo, Xinyu
collection PubMed
description Biomimetic materials are able to mimic the structure and functional properties of native tissues especially natural oral tissues. They have attracted growing attention for their potential to achieve configurable and functional reconstruction in oral medicine. Though tremendous progress has been made regarding biomimetic materials, significant challenges still remain in terms of controversy on the mechanism of tooth tissue regeneration, lack of options for manufacturing such materials and insufficiency of in vivo experimental tests in related fields. In this review, the biomimetic materials used in oral medicine are summarized systematically, including tooth defect, tooth loss, periodontal diseases and maxillofacial bone defect. Various theoretical foundations of biomimetic materials research are reviewed, introducing the current and pertinent results. The benefits and limitations of these materials are summed up at the same time. Finally, challenges and potential of this field are discussed. This review provides the framework and support for further research in addition to giving a generally novel and fundamental basis for the utilization of biomimetic materials in the future.
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spelling pubmed-106683812023-11-23 Research progress of biomimetic materials in oral medicine Luo, Xinyu Niu, Jiayue Su, Guanyu Zhou, Linxi Zhang, Xue Liu, Ying Wang, Qiang Sun, Ningning J Biol Eng Review Biomimetic materials are able to mimic the structure and functional properties of native tissues especially natural oral tissues. They have attracted growing attention for their potential to achieve configurable and functional reconstruction in oral medicine. Though tremendous progress has been made regarding biomimetic materials, significant challenges still remain in terms of controversy on the mechanism of tooth tissue regeneration, lack of options for manufacturing such materials and insufficiency of in vivo experimental tests in related fields. In this review, the biomimetic materials used in oral medicine are summarized systematically, including tooth defect, tooth loss, periodontal diseases and maxillofacial bone defect. Various theoretical foundations of biomimetic materials research are reviewed, introducing the current and pertinent results. The benefits and limitations of these materials are summed up at the same time. Finally, challenges and potential of this field are discussed. This review provides the framework and support for further research in addition to giving a generally novel and fundamental basis for the utilization of biomimetic materials in the future. BioMed Central 2023-11-23 /pmc/articles/PMC10668381/ /pubmed/37996886 http://dx.doi.org/10.1186/s13036-023-00382-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Luo, Xinyu
Niu, Jiayue
Su, Guanyu
Zhou, Linxi
Zhang, Xue
Liu, Ying
Wang, Qiang
Sun, Ningning
Research progress of biomimetic materials in oral medicine
title Research progress of biomimetic materials in oral medicine
title_full Research progress of biomimetic materials in oral medicine
title_fullStr Research progress of biomimetic materials in oral medicine
title_full_unstemmed Research progress of biomimetic materials in oral medicine
title_short Research progress of biomimetic materials in oral medicine
title_sort research progress of biomimetic materials in oral medicine
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668381/
https://www.ncbi.nlm.nih.gov/pubmed/37996886
http://dx.doi.org/10.1186/s13036-023-00382-4
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