Cargando…

Value of inferior vena cava collapsibility index as marker of heart failure in chronic obstructive pulmonary disease exacerbation

INTRODUCTION: Inferior vena cava (IVC) diameter variability with respiration measured by ultrasound was found to be useful for the diagnosis of heart failure (HF) in ED patients with acute dyspnea. Its value in identifying HF in acute exacerbation of chronic obstructive pulmonary disease exacerbatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Kouraichi, Cyrine, Sekma, Adel, Bel Haj Ali, Khaoula, Chamtouri, Ikram, Sassi, Sarra, Toumia, Marwa, Yaakoubi, Hajer, Youssef, Rym, Msolli, Mohamed Amine, Beltaief, Kaouthar, Mezgar, Zied, Khrouf, Mariem, Bouida, Wahid, Dridi, Zohra, Boukef, Riadh, Boubaker, Hamdi, Grissa, Mohamed Habib, Nouira, Semir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668419/
https://www.ncbi.nlm.nih.gov/pubmed/37996792
http://dx.doi.org/10.1186/s12872-023-03585-1
_version_ 1785149126702268416
author Kouraichi, Cyrine
Sekma, Adel
Bel Haj Ali, Khaoula
Chamtouri, Ikram
Sassi, Sarra
Toumia, Marwa
Yaakoubi, Hajer
Youssef, Rym
Msolli, Mohamed Amine
Beltaief, Kaouthar
Mezgar, Zied
Khrouf, Mariem
Bouida, Wahid
Dridi, Zohra
Boukef, Riadh
Boubaker, Hamdi
Grissa, Mohamed Habib
Nouira, Semir
author_facet Kouraichi, Cyrine
Sekma, Adel
Bel Haj Ali, Khaoula
Chamtouri, Ikram
Sassi, Sarra
Toumia, Marwa
Yaakoubi, Hajer
Youssef, Rym
Msolli, Mohamed Amine
Beltaief, Kaouthar
Mezgar, Zied
Khrouf, Mariem
Bouida, Wahid
Dridi, Zohra
Boukef, Riadh
Boubaker, Hamdi
Grissa, Mohamed Habib
Nouira, Semir
author_sort Kouraichi, Cyrine
collection PubMed
description INTRODUCTION: Inferior vena cava (IVC) diameter variability with respiration measured by ultrasound was found to be useful for the diagnosis of heart failure (HF) in ED patients with acute dyspnea. Its value in identifying HF in acute exacerbation of chronic obstructive pulmonary disease exacerbation (AECOPD) was not specifically demonstrated. OBJECTIVE: To determine the value of ΔIVC in the diagnosis of HF patients with AECOPD. METHODS: This is a prospective study conducted in the ED of three Tunisian university hospitals including patients with AECOPD. During this period, 401 patients met the inclusion criteria. The final diagnosis of HF is based on the opinion of two emergency experts after consulting the data from clinical examination, cardiac echocardiography, and BNP level. The ΔIVC was calculated by two experienced emergency physicians who were blinded from the patient’s clinical and laboratory data. A cut off of 15% was used to define the presence (< 15%) or absence of HF (≥ 15%). Left ventricular ejection fraction (LVEF) was also measured. The area under the ROC curve, sensitivity, specificity, and positive and negative predictive values were calculated to determine the diagnostic and predictive accuracy of the ΔIVC in predicting HF. RESULTS: The study population included 401 patients with AECOPD, mean age 67.2 years with male (68.9%) predominance. HF was diagnosed in 165 (41.1%) patients (HF group) and in 236 patients (58.9%) HF was excluded (non HF group). The assessment of the performance of the ΔIVC in the diagnosis of HF showed a sensitivity of 37.4% and a specificity of 89.7% using the threshold of 15%. The positive predictive value was 70.9% and the negative predictive value was 66.7%. The area under the ROC curve was 0.71(95%, CI 0.65–0.76). ΔIVC values were not different between HF patients with reduced LVEF and those with preserved LVEF. CONCLUSION: Our results showed that ΔIVC has a good value for ruling out HF in ED patients consulting for AECOPD.
format Online
Article
Text
id pubmed-10668419
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-106684192023-11-24 Value of inferior vena cava collapsibility index as marker of heart failure in chronic obstructive pulmonary disease exacerbation Kouraichi, Cyrine Sekma, Adel Bel Haj Ali, Khaoula Chamtouri, Ikram Sassi, Sarra Toumia, Marwa Yaakoubi, Hajer Youssef, Rym Msolli, Mohamed Amine Beltaief, Kaouthar Mezgar, Zied Khrouf, Mariem Bouida, Wahid Dridi, Zohra Boukef, Riadh Boubaker, Hamdi Grissa, Mohamed Habib Nouira, Semir BMC Cardiovasc Disord Research INTRODUCTION: Inferior vena cava (IVC) diameter variability with respiration measured by ultrasound was found to be useful for the diagnosis of heart failure (HF) in ED patients with acute dyspnea. Its value in identifying HF in acute exacerbation of chronic obstructive pulmonary disease exacerbation (AECOPD) was not specifically demonstrated. OBJECTIVE: To determine the value of ΔIVC in the diagnosis of HF patients with AECOPD. METHODS: This is a prospective study conducted in the ED of three Tunisian university hospitals including patients with AECOPD. During this period, 401 patients met the inclusion criteria. The final diagnosis of HF is based on the opinion of two emergency experts after consulting the data from clinical examination, cardiac echocardiography, and BNP level. The ΔIVC was calculated by two experienced emergency physicians who were blinded from the patient’s clinical and laboratory data. A cut off of 15% was used to define the presence (< 15%) or absence of HF (≥ 15%). Left ventricular ejection fraction (LVEF) was also measured. The area under the ROC curve, sensitivity, specificity, and positive and negative predictive values were calculated to determine the diagnostic and predictive accuracy of the ΔIVC in predicting HF. RESULTS: The study population included 401 patients with AECOPD, mean age 67.2 years with male (68.9%) predominance. HF was diagnosed in 165 (41.1%) patients (HF group) and in 236 patients (58.9%) HF was excluded (non HF group). The assessment of the performance of the ΔIVC in the diagnosis of HF showed a sensitivity of 37.4% and a specificity of 89.7% using the threshold of 15%. The positive predictive value was 70.9% and the negative predictive value was 66.7%. The area under the ROC curve was 0.71(95%, CI 0.65–0.76). ΔIVC values were not different between HF patients with reduced LVEF and those with preserved LVEF. CONCLUSION: Our results showed that ΔIVC has a good value for ruling out HF in ED patients consulting for AECOPD. BioMed Central 2023-11-24 /pmc/articles/PMC10668419/ /pubmed/37996792 http://dx.doi.org/10.1186/s12872-023-03585-1 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Kouraichi, Cyrine
Sekma, Adel
Bel Haj Ali, Khaoula
Chamtouri, Ikram
Sassi, Sarra
Toumia, Marwa
Yaakoubi, Hajer
Youssef, Rym
Msolli, Mohamed Amine
Beltaief, Kaouthar
Mezgar, Zied
Khrouf, Mariem
Bouida, Wahid
Dridi, Zohra
Boukef, Riadh
Boubaker, Hamdi
Grissa, Mohamed Habib
Nouira, Semir
Value of inferior vena cava collapsibility index as marker of heart failure in chronic obstructive pulmonary disease exacerbation
title Value of inferior vena cava collapsibility index as marker of heart failure in chronic obstructive pulmonary disease exacerbation
title_full Value of inferior vena cava collapsibility index as marker of heart failure in chronic obstructive pulmonary disease exacerbation
title_fullStr Value of inferior vena cava collapsibility index as marker of heart failure in chronic obstructive pulmonary disease exacerbation
title_full_unstemmed Value of inferior vena cava collapsibility index as marker of heart failure in chronic obstructive pulmonary disease exacerbation
title_short Value of inferior vena cava collapsibility index as marker of heart failure in chronic obstructive pulmonary disease exacerbation
title_sort value of inferior vena cava collapsibility index as marker of heart failure in chronic obstructive pulmonary disease exacerbation
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668419/
https://www.ncbi.nlm.nih.gov/pubmed/37996792
http://dx.doi.org/10.1186/s12872-023-03585-1
work_keys_str_mv AT kouraichicyrine valueofinferiorvenacavacollapsibilityindexasmarkerofheartfailureinchronicobstructivepulmonarydiseaseexacerbation
AT sekmaadel valueofinferiorvenacavacollapsibilityindexasmarkerofheartfailureinchronicobstructivepulmonarydiseaseexacerbation
AT belhajalikhaoula valueofinferiorvenacavacollapsibilityindexasmarkerofheartfailureinchronicobstructivepulmonarydiseaseexacerbation
AT chamtouriikram valueofinferiorvenacavacollapsibilityindexasmarkerofheartfailureinchronicobstructivepulmonarydiseaseexacerbation
AT sassisarra valueofinferiorvenacavacollapsibilityindexasmarkerofheartfailureinchronicobstructivepulmonarydiseaseexacerbation
AT toumiamarwa valueofinferiorvenacavacollapsibilityindexasmarkerofheartfailureinchronicobstructivepulmonarydiseaseexacerbation
AT yaakoubihajer valueofinferiorvenacavacollapsibilityindexasmarkerofheartfailureinchronicobstructivepulmonarydiseaseexacerbation
AT youssefrym valueofinferiorvenacavacollapsibilityindexasmarkerofheartfailureinchronicobstructivepulmonarydiseaseexacerbation
AT msollimohamedamine valueofinferiorvenacavacollapsibilityindexasmarkerofheartfailureinchronicobstructivepulmonarydiseaseexacerbation
AT beltaiefkaouthar valueofinferiorvenacavacollapsibilityindexasmarkerofheartfailureinchronicobstructivepulmonarydiseaseexacerbation
AT mezgarzied valueofinferiorvenacavacollapsibilityindexasmarkerofheartfailureinchronicobstructivepulmonarydiseaseexacerbation
AT khroufmariem valueofinferiorvenacavacollapsibilityindexasmarkerofheartfailureinchronicobstructivepulmonarydiseaseexacerbation
AT bouidawahid valueofinferiorvenacavacollapsibilityindexasmarkerofheartfailureinchronicobstructivepulmonarydiseaseexacerbation
AT dridizohra valueofinferiorvenacavacollapsibilityindexasmarkerofheartfailureinchronicobstructivepulmonarydiseaseexacerbation
AT boukefriadh valueofinferiorvenacavacollapsibilityindexasmarkerofheartfailureinchronicobstructivepulmonarydiseaseexacerbation
AT boubakerhamdi valueofinferiorvenacavacollapsibilityindexasmarkerofheartfailureinchronicobstructivepulmonarydiseaseexacerbation
AT grissamohamedhabib valueofinferiorvenacavacollapsibilityindexasmarkerofheartfailureinchronicobstructivepulmonarydiseaseexacerbation
AT nouirasemir valueofinferiorvenacavacollapsibilityindexasmarkerofheartfailureinchronicobstructivepulmonarydiseaseexacerbation