Acute expression of human APOBEC3B in mice results in RNA editing and lethality

BACKGROUND: RNA editing has been described as promoting genetic heterogeneity, leading to the development of multiple disorders, including cancer. The cytosine deaminase APOBEC3B is implicated in tumor evolution through DNA mutation, but whether it also functions as an RNA editing enzyme has not bee...

Descripción completa

Detalles Bibliográficos
Autores principales: Alonso de la Vega, Alicia, Temiz, Nuri Alpay, Tasakis, Rafail, Somogyi, Kalman, Salgueiro, Lorena, Zimmer, Eleni, Ramos, Maria, Diaz-Jimenez, Alberto, Chocarro, Sara, Fernández-Vaquero, Mirian, Stefanovska, Bojana, Reuveni, Eli, Ben-David, Uri, Stenzinger, Albrecht, Poth, Tanja, Heikenwälder, Mathias, Papavasiliou, Nina, Harris, Reuben S., Sotillo, Rocio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668425/
https://www.ncbi.nlm.nih.gov/pubmed/38001542
http://dx.doi.org/10.1186/s13059-023-03115-4

Ejemplares similares

Ejemplares similares