Cargando…

Parathyroid hormone stimulates bone regeneration in an atrophic non-union model in aged mice

BACKGROUND: Non-union formation still represents a major burden in trauma and orthopedic surgery. Moreover, aged patients are at an increased risk for bone healing failure. Parathyroid hormone (PTH) has been shown to accelerate fracture healing in young adult animals. However, there is no informatio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Menger, Maximilian M., Tobias, Anne L., Bauer, David, Bleimehl, Michelle, Scheuer, Claudia, Menger, Michael D., Histing, Tina, Laschke, Matthias W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668449/ https://www.ncbi.nlm.nih.gov/pubmed/37996876 http://dx.doi.org/10.1186/s12967-023-04661-y

Ejemplares similares

Sildenafil, a phosphodiesterase-5 inhibitor, stimulates angiogenesis and bone regeneration in an atrophic non-union model in mice
por: Menger, Maximilian M., et al.
Publicado: (2023)

Photoacoustic imaging for the study of oxygen saturation and total hemoglobin in bone healing and non-union formation
por: Menger, Maximilian M., et al.
Publicado: (2022)

The vascularization paradox of non-union formation
por: Menger, Maximilian M., et al.
Publicado: (2022)

Bone Healing Gone Wrong: Pathological Fracture Healing and Non-Unions—Overview of Basic and Clinical Aspects and Systematic Review of Risk Factors
por: Saul, Dominik, et al.
Publicado: (2023)

Atrophe Pseudarthrose des Sternums – ein Fallbericht orientiert am Non Union Scoring System
por: Braun, Benedikt J., et al.
Publicado: (2022)

Profiling microRNA expression in murine bone healing and non-union formation: Role of miR-140 during the early stage of bone healing
por: Orth, Marcel, et al.
Publicado: (2019)

Local Application of Mineral-Coated Microparticles Loaded With VEGF and BMP-2 Induces the Healing of Murine Atrophic Non-Unions
por: Orth, M., et al.
Publicado: (2022)

Incorporation of Bone Marrow Cells in Pancreatic Pseudoislets Improves Posttransplant Vascularization and Endocrine Function
por: Wittig, Christine, et al.
Publicado: (2013)

Radiographic, Biomechanical and Histological Characterization of Femoral Fracture Healing in Aged CD-1 Mice
por: Menger, Maximilian M., et al.
Publicado: (2023)

Insulin-like growth factor 1 stimulates the angiogenic activity of adipose tissue–derived microvascular fragments
por: Laschke, Matthias W, et al.
Publicado: (2019)

Tubeimoside-1 suppresses tumor angiogenesis by stimulation of proteasomal VEGFR2 and Tie2 degradation in a non-small cell lung cancer xenograft model
por: Gu, Yuan, et al.
Publicado: (2015)

Geraniol Suppresses Angiogenesis by Downregulating Vascular Endothelial Growth Factor (VEGF)/VEGFR-2 Signaling
por: Wittig, Christine, et al.
Publicado: (2015)

Indole-3-Carbinol Inhibits the Growth of Endometriotic Lesions by Suppression of Microvascular Network Formation
por: Rudzitis-Auth, Jeannette, et al.
Publicado: (2022)

Pantoprazole impairs fracture healing in aged mice
por: Menger, Maximilian M., et al.
Publicado: (2020)

Macrophages promote network formation and maturation of transplanted adipose tissue–derived microvascular fragments
por: Später, Thomas, et al.
Publicado: (2020)

Systemic low-dose erythropoietin administration improves the vascularization of collagen-glycosaminoglycan matrices seeded with adipose tissue-derived microvascular fragments
por: Später, Thomas, et al.
Publicado: (2021)

The ischemic time window of ectopic endometrial tissue crucially determines its ability to develop into endometriotic lesions
por: Rudzitis-Auth, Jeannette, et al.
Publicado: (2022)

Erythropoietin exposure of isolated pancreatic islets accelerates their revascularization after transplantation
por: Menger, Maximilian M., et al.
Publicado: (2021)

Correction to: Darbepoetin-α increases the blood volume flow in transplanted pancreatic islets in mice
por: Menger, Maximilian M., et al.
Publicado: (2021)

Darbepoetin-α increases the blood volume flow in transplanted pancreatic islets in mice
por: Menger, Maximilian M., et al.
Publicado: (2020)

Microvascular fragment spheroids: Three-dimensional vascularization units for tissue engineering and regeneration
por: Nalbach, Lisa, et al.
Publicado: (2021)

Osteolectin(+) stromal cells: Mechanical stimulation improves bone regeneration and supports bacterial clearance after fracture
por: Ehnert, Sabrina, et al.
Publicado: (2021)

Portal Hyperperfusion after Extended Hepatectomy Does Not Induce a Hepatic Arterial Buffer Response (HABR) but Impairs Mitochondrial Redox State and Hepatocellular Oxygenation
por: Dold, Stefan, et al.
Publicado: (2015)

Caloric Restriction: A Novel Conditioning Strategy to Improve the Survival of Ischemically Challenged Musculocutaneous Random Pattern Flaps
por: Weinzierl, Andrea, et al.
Publicado: (2023)

Replacement in angiogenesis research: Studying mechanisms of blood vessel development by animal-free in vitro, in vivo and in silico approaches
por: Laschke, Matthias W., et al.
Publicado: (2022)

Occurrence and Treatment of Bone Atrophic Non-Unions Investigated by an Integrative Approach
por: Geris, Liesbet, et al.
Publicado: (2010)

3D Environment Is Required In Vitro to Demonstrate Altered Bone Metabolism Characteristic for Type 2 Diabetics
por: Häussling, Victor, et al.
Publicado: (2021)

Influence of Parathyroid Hormone-Loaded PLGA Nanoparticles in Porous Scaffolds for Bone Regeneration
por: Gentile, Piergiorgio, et al.
Publicado: (2015)

Fractures of the femoral head: a narrative review
por: Menger, Maximilian M., et al.
Publicado: (2021)

Development of an ischemic fracture healing model in mice
por: MENGER, Maximilian M, et al.
Publicado: (2022)

Prevascularization of dermal substitutes with adipose tissue-derived microvascular fragments enhances early skin grafting
por: Frueh, Florian S., et al.
Publicado: (2018)

Luminal epithelium in endometrial fragments affects their vascularization, growth and morphological development into endometriosis-like lesions in mice
por: Feng, Dilu, et al.
Publicado: (2014)

Regulatory Mechanisms of Somatostatin Expression
por: Ampofo, Emmanuel, et al.
Publicado: (2020)

Combining Vascularization Strategies in Tissue Engineering: The Faster Road to Success?
por: Später, Thomas, et al.
Publicado: (2020)

Tissue-Protective Mechanisms of Bioactive Phytochemicals in Flap Surgery
por: Weinzierl, Andrea, et al.
Publicado: (2022)

Translational evaluation of gait behavior in rodent models of arthritic disorders with the CatWalk device – a narrative review
por: Ritter, Jana, et al.
Publicado: (2023)

The regulatory mechanisms of NG2/CSPG4 expression
por: Ampofo, Emmanuel, et al.
Publicado: (2017)

Maslinic acid alleviates ischemia/reperfusion-induced inflammation by downregulation of NFκB-mediated adhesion molecule expression
por: Ampofo, Emmanuel, et al.
Publicado: (2019)

The Presence of Pre-Existing Endometriotic Lesions Promotes the Growth of New Lesions in the Peritoneal Cavity
por: Mihai, Ilinca T., et al.
Publicado: (2023)

Intermittent Exposure to a 16 Hz Extremely Low Frequency Pulsed Electromagnetic Field Promotes Osteogenesis In Vitro through Activating Piezo 1-Induced Ca(2+) Influx in Osteoprogenitor Cells
por: Chen, Yangmengfan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_gn4dfvtuljgp0u88j3ii7nf72a