Molecular characterization of the CXCR4 / CXCR7 axis in germ cell tumors and its targetability using nanobody-drug-conjugates

Being stimulated by the chemokine CXCL12, the CXCR4 / CXCR7 cascade is involved in tumor proliferation, migration, and metastasis. The interaction between CXCL12, secreted by cells from the microenvironment, and its receptors is complex and has been ascribed to promote chemotherapy resistance. Howev...

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Detalles Bibliográficos
Autores principales: Wakileh, Gamal A., Bierholz, Philipp, Kotthoff, Mara, Skowron, Margaretha A., Bremmer, Felix, Stephan, Alexa, Anbuhl, Stephanie M., Heukers, Raimond, Smit, Martine J., Ströbel, Philipp, Nettersheim, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668499/
https://www.ncbi.nlm.nih.gov/pubmed/37996954
http://dx.doi.org/10.1186/s40164-023-00460-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668499/
https://www.ncbi.nlm.nih.gov/pubmed/37996954
http://dx.doi.org/10.1186/s40164-023-00460-9

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