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PSMC5 regulates microglial polarization and activation in LPS-induced cognitive deficits and motor impairments by interacting with TLR4

Luteolin is a flavonoid found in high concentrations in celery and green pepper, and acts as a neuroprotectant. PSMC5 (proteasome 26S subunit, ATPase 5) protein levels were reduced after luteolin stimulation in activated microglia. We aimed to determine whether regulating PSMC5 expression could inhi...

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Detalles Bibliográficos
Autores principales: Bi, Wei, Bao, Keyao, Zhou, Xinqi, Deng, Yihui, Li, Xiaoting, Zhang, Jiawei, Lan, Xin, Zhao, Jiayi, Lu, Daxiang, Xu, Yezi, Cen, Yanmei, Cao, Rui, Xu, Mengyang, Zhong, Wenbin, Zhu, Lihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668523/
https://www.ncbi.nlm.nih.gov/pubmed/38001534
http://dx.doi.org/10.1186/s12974-023-02904-9