Cargando…

PSMC5 regulates microglial polarization and activation in LPS-induced cognitive deficits and motor impairments by interacting with TLR4

Luteolin is a flavonoid found in high concentrations in celery and green pepper, and acts as a neuroprotectant. PSMC5 (proteasome 26S subunit, ATPase 5) protein levels were reduced after luteolin stimulation in activated microglia. We aimed to determine whether regulating PSMC5 expression could inhi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bi, Wei, Bao, Keyao, Zhou, Xinqi, Deng, Yihui, Li, Xiaoting, Zhang, Jiawei, Lan, Xin, Zhao, Jiayi, Lu, Daxiang, Xu, Yezi, Cen, Yanmei, Cao, Rui, Xu, Mengyang, Zhong, Wenbin, Zhu, Lihong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668523/ https://www.ncbi.nlm.nih.gov/pubmed/38001534 http://dx.doi.org/10.1186/s12974-023-02904-9

Ejemplares similares

Knockdown of PSMC2 contributes to suppression of cholangiocarcinoma development by regulating CDK1
por: Duan, Xiaohui, et al.
Publicado: (2021)

circPSMC3: ceRNA and tumor suppressor
por: Lu, Chen, et al.
Publicado: (2019)

DHZCP Modulates Microglial M1/M2 Polarization via the p38 and TLR4/NF-κB Signaling Pathways in LPS-Stimulated Microglial Cells
por: Zhou, Lu, et al.
Publicado: (2020)

LPS induces microglial activation and GABAergic synaptic deficits in the hippocampus accompanied by prolonged cognitive impairment
por: Jung, Hyeji, et al.
Publicado: (2023)

PSMC1 variant causes a novel neurological syndrome
por: Aharoni, Sarit, et al.
Publicado: (2022)

PSMC2 knockdown suppressed tumor progression of skin cutaneous melanoma
por: Yang, Yanwen, et al.
Publicado: (2021)

The Silence of PSMC6 Inhibits Cell Growth and Metastasis in Lung Adenocarcinoma
por: Zhang, Jian-Yu, et al.
Publicado: (2021)

PSMC2 is overexpressed in glioma and promotes proliferation and anti-apoptosis of glioma cells
por: Zheng, Xiaoyang, et al.
Publicado: (2022)

Beta-PSMC: uncovering more detailed population history using beta distribution
por: Liu, Junfeng, et al.
Publicado: (2022)

Rifampicin improves neuronal apoptosis in LPS-stimulated co-cultured BV2 cells through inhibition of the TLR-4 pathway
por: BI, WEI, et al.
Publicado: (2014)

Transcriptome sequencing of microglial cells stimulated with TLR3 and TLR4 ligands
por: Das, Amitabh, et al.
Publicado: (2015)

Microglial activation by microbial neuraminidase through TLR2 and TLR4 receptors
por: Fernández-Arjona, María del Mar, et al.
Publicado: (2019)

PSMC5, a 19S Proteasomal ATPase, Regulates Cocaine Action in the Nucleus Accumbens
por: Ohnishi, Yoko H., et al.
Publicado: (2015)

PSMC2 is up-regulated in osteosarcoma and regulates osteosarcoma cell proliferation, apoptosis and migration
por: Song, Mingzhi, et al.
Publicado: (2016)

PSMC3 promotes RNAi by maintaining AGO2 stability through USP14
por: Jia, Yan, et al.
Publicado: (2022)

PSMC2 is a Novel Prognostic Biomarker and Predicts Immunotherapeutic Responses: From Pancreatic Cancer to Pan-Cancer
por: Huang, Wei, et al.
Publicado: (2023)

Correction: PSMC5, a 19S Proteasomal ATPase, Regulates Cocaine Action in the Nucleus Accumbens
por: Ohnishi, Yoko H., et al.
Publicado: (2015)

PSMC2 is Up-regulated in Pancreatic Cancer and Promotes Cancer Cell Proliferation and Inhibits Apoptosis
por: Qin, Jing, et al.
Publicado: (2019)

PSMC2/ITGA6 axis plays critical role in the development and progression of hepatocellular carcinoma
por: Duan, Xuhua, et al.
Publicado: (2021)

Cascade Signals of Papaverine Inhibiting LPS-Induced Retinal Microglial Activation
por: Zhou, Ting, et al.
Publicado: (2019)

Hydroxytyrosol Decreases LPS- and α-Synuclein-Induced Microglial Activation In Vitro
por: Gallardo-Fernández, Marta, et al.
Publicado: (2019)

Epiisopiloturine, an Alkaloid from Pilocarpus microphyllus, Attenuates LPS-Induced Neuroinflammation by Interfering in the TLR4/NF-κB-MAPK Signaling Pathway in Microglial Cells
por: de Sousa, João Antônio Costa, et al.
Publicado: (2023)

Association between TLR4 and PTEN Involved in LPS-TLR4 Signaling Response
por: Yin, Huahua, et al.
Publicado: (2016)

TLR4 Response to LPS Is Reinforced by Urokinase Receptor
por: Kiyan, Yulia, et al.
Publicado: (2020)

Breast Cancer Genes PSMC3IP and EPSTI1 Play a Role in Apoptosis Regulation
por: Capdevila-Busquets, Eva, et al.
Publicado: (2015)

PSMC analysis of effective population sizes in molecular ecology and its application to black‐and‐white Ficedula flycatchers
por: Nadachowska‐Brzyska, Krystyna, et al.
Publicado: (2016)

Prognoses and genomic analyses of proteasome 26S subunit, ATPase (PSMC) family genes in clinical breast cancer
por: Kao, Tzu-Jen, et al.
Publicado: (2021)

Silencing of PSMC2 inhibits development and metastasis of prostate cancer through regulating proliferation, apoptosis and migration
por: Chen, Qingke, et al.
Publicado: (2021)

Effects of Betaine on LPS-Stimulated Activation of Microglial M1/M2 Phenotypes by Suppressing TLR4/NF-κB Pathways in N9 Cells
por: Shi, Hui, et al.
Publicado: (2019)

Okanin, effective constituent of the flower tea Coreopsis tinctoria, attenuates LPS-induced microglial activation through inhibition of the TLR4/NF-κB signaling pathways
por: Hou, Yue, et al.
Publicado: (2017)

Genistein Attenuates Isoflurane-Induced Neuroinflammation by Inhibiting TLR4-Mediated Microglial-Polarization in vivo and in vitro
por: Jiang, Tao, et al.
Publicado: (2021)

TLR4 mutation reduces microglial activation, increases Aβ deposits and exacerbates cognitive deficits in a mouse model of Alzheimer's disease
por: Song, Min, et al.
Publicado: (2011)

Rhodobacter azotoformans LPS (RAP99-LPS) Is a TLR4 Agonist That Inhibits Lung Metastasis and Enhances TLR3-Mediated Chemokine Expression
por: Murakami, Kaoru, et al.
Publicado: (2021)

Induction of TLR4/TLR2 Interaction and Heterodimer Formation by Low Endotoxic Atypical LPS
por: Francisco, Sara, et al.
Publicado: (2022)

Natural Potent NAAA Inhibitor Atractylodin Counteracts LPS-Induced Microglial Activation
por: Yang, Longhe, et al.
Publicado: (2020)

Anti-Inflammatory Activity of Panduratin A against LPS-Induced Microglial Activation
por: Jamornwan, Sopana, et al.
Publicado: (2022)

Inhibition of LPS-Induced Microglial Activation by the Ethyl Acetate Extract of Pueraria mirifica
por: Jantaratnotai, Nattinee, et al.
Publicado: (2022)

PACAP and VIP Modulate LPS-Induced Microglial Activation and Trigger Distinct Phenotypic Changes in Murine BV2 Microglial Cells
por: Karunia, Jocelyn, et al.
Publicado: (2021)

From monogenic lupus to TLR7/MyD88-targeted therapy
por: Wang, Min, et al.
Publicado: (2022)

Glucosylceramide modifies the LPS-induced inflammatory response in macrophages and the orientation of the LPS/TLR4 complex in silico
por: Mobarak, Edouard, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_k2rn91md7jdd7ju53t439qml2f