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Senescent Endothelial Cells Sustain Their Senescence-Associated Secretory Phenotype (SASP) through Enhanced Fatty Acid Oxidation

Cellular senescence is closely linked to endothelial dysfunction, a key factor in age-related vascular diseases. Senescent endothelial cells exhibit a proinflammatory phenotype known as SASP, leading to chronic inflammation (inflammaging) and vascular impairments. Albeit in a state of permanent grow...

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Detalles Bibliográficos
Autores principales: Giuliani, Angelica, Giudetti, Anna Maria, Vergara, Daniele, Del Coco, Laura, Ramini, Deborah, Caccese, Sara, Sbriscia, Matilde, Graciotti, Laura, Fulgenzi, Gianluca, Tiano, Luca, Fanizzi, Francesco Paolo, Olivieri, Fabiola, Rippo, Maria Rita, Sabbatinelli, Jacopo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668971/
https://www.ncbi.nlm.nih.gov/pubmed/38001810
http://dx.doi.org/10.3390/antiox12111956

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