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Molecular Cloning, Heterologous Expression, Purification, and Evaluation of Protein–Ligand Interactions of CYP51 of Candida krusei Azole-Resistant Fungal Strain

Due to the increasing prevalence of fungal diseases caused by fungi of the genus Candida and the development of pathogen resistance to available drugs, the need to find new effective antifungal agents has increased. Azole antifungals, which are inhibitors of sterol-14α-demethylase or CYP51, have bee...

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Detalles Bibliográficos
Autores principales:	Tsybruk, Tatsiana V., Kaluzhskiy, Leonid A., Mezentsev, Yuri V., Makarieva, Tatyana N., Tabakmaher, Kseniya M., Ivanchina, Natalia V., Dmitrenok, Pavel S., Baranovsky, Alexander V., Gilep, Andrei A., Ivanov, Alexis S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668980/ https://www.ncbi.nlm.nih.gov/pubmed/38001874 http://dx.doi.org/10.3390/biomedicines11112873

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