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Exploiting TLK1 and Cisplatin Synergy for Synthetic Lethality in Androgen-Insensitive Prostate Cancer

Cellular organisms possess intricate DNA damage repair and tolerance pathways to manage various DNA lesions arising from endogenous or exogenous sources. The dysregulation of these pathways is associated with cancer development and progression. Synthetic lethality (SL), a promising cancer therapy co...

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Detalles Bibliográficos
Autores principales:	Bhoir, Siddhant, Ogundepo, Oluwatobi, Yu, Xiuping, Shi, Runhua, De Benedetti, Arrigo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669050/ https://www.ncbi.nlm.nih.gov/pubmed/38001987 http://dx.doi.org/10.3390/biomedicines11112987

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