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Peak Bone Mass Formation: Modern View of the Problem
Peak bone mass is the amount of bone tissue that is formed when a stable skeletal state is achieved at a young age. To date, there are no established peak bone mass standards nor clear data on the age at which peak bone mass occurs. At the same time, the level of peak bone mass at a young age is an...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669090/ https://www.ncbi.nlm.nih.gov/pubmed/38001982 http://dx.doi.org/10.3390/biomedicines11112982 |
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author | Akhiiarova, Karina Khusainova, Rita Minniakhmetov, Ildar Mokrysheva, Natalia Tyurin, Anton |
author_facet | Akhiiarova, Karina Khusainova, Rita Minniakhmetov, Ildar Mokrysheva, Natalia Tyurin, Anton |
author_sort | Akhiiarova, Karina |
collection | PubMed |
description | Peak bone mass is the amount of bone tissue that is formed when a stable skeletal state is achieved at a young age. To date, there are no established peak bone mass standards nor clear data on the age at which peak bone mass occurs. At the same time, the level of peak bone mass at a young age is an important predictor of the onset of primary osteoporosis. The purpose of this review is to analyze the results of studies of levels of peak bone mass in general, the age of its onset, as well as factors influencing its formation. Factors such as hormonal levels, body composition, physical activity, nutrition, heredity, smoking, lifestyle, prenatal predictors, intestinal microbiota, and vitamin and micronutrient status were considered, and a comprehensive scheme of the influence of these factors on the level of peak bone mass was created. Determining the standards and timing of the formation of peak bone mass, and the factors affecting it, will help in the development of measures to prevent its shortage and the consequent prevention of osteoporosis and concomitant diseases. |
format | Online Article Text |
id | pubmed-10669090 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-106690902023-11-06 Peak Bone Mass Formation: Modern View of the Problem Akhiiarova, Karina Khusainova, Rita Minniakhmetov, Ildar Mokrysheva, Natalia Tyurin, Anton Biomedicines Review Peak bone mass is the amount of bone tissue that is formed when a stable skeletal state is achieved at a young age. To date, there are no established peak bone mass standards nor clear data on the age at which peak bone mass occurs. At the same time, the level of peak bone mass at a young age is an important predictor of the onset of primary osteoporosis. The purpose of this review is to analyze the results of studies of levels of peak bone mass in general, the age of its onset, as well as factors influencing its formation. Factors such as hormonal levels, body composition, physical activity, nutrition, heredity, smoking, lifestyle, prenatal predictors, intestinal microbiota, and vitamin and micronutrient status were considered, and a comprehensive scheme of the influence of these factors on the level of peak bone mass was created. Determining the standards and timing of the formation of peak bone mass, and the factors affecting it, will help in the development of measures to prevent its shortage and the consequent prevention of osteoporosis and concomitant diseases. MDPI 2023-11-06 /pmc/articles/PMC10669090/ /pubmed/38001982 http://dx.doi.org/10.3390/biomedicines11112982 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Akhiiarova, Karina Khusainova, Rita Minniakhmetov, Ildar Mokrysheva, Natalia Tyurin, Anton Peak Bone Mass Formation: Modern View of the Problem |
title | Peak Bone Mass Formation: Modern View of the Problem |
title_full | Peak Bone Mass Formation: Modern View of the Problem |
title_fullStr | Peak Bone Mass Formation: Modern View of the Problem |
title_full_unstemmed | Peak Bone Mass Formation: Modern View of the Problem |
title_short | Peak Bone Mass Formation: Modern View of the Problem |
title_sort | peak bone mass formation: modern view of the problem |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669090/ https://www.ncbi.nlm.nih.gov/pubmed/38001982 http://dx.doi.org/10.3390/biomedicines11112982 |
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