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Peak Bone Mass Formation: Modern View of the Problem

Peak bone mass is the amount of bone tissue that is formed when a stable skeletal state is achieved at a young age. To date, there are no established peak bone mass standards nor clear data on the age at which peak bone mass occurs. At the same time, the level of peak bone mass at a young age is an...

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Autores principales: Akhiiarova, Karina, Khusainova, Rita, Minniakhmetov, Ildar, Mokrysheva, Natalia, Tyurin, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669090/
https://www.ncbi.nlm.nih.gov/pubmed/38001982
http://dx.doi.org/10.3390/biomedicines11112982
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author Akhiiarova, Karina
Khusainova, Rita
Minniakhmetov, Ildar
Mokrysheva, Natalia
Tyurin, Anton
author_facet Akhiiarova, Karina
Khusainova, Rita
Minniakhmetov, Ildar
Mokrysheva, Natalia
Tyurin, Anton
author_sort Akhiiarova, Karina
collection PubMed
description Peak bone mass is the amount of bone tissue that is formed when a stable skeletal state is achieved at a young age. To date, there are no established peak bone mass standards nor clear data on the age at which peak bone mass occurs. At the same time, the level of peak bone mass at a young age is an important predictor of the onset of primary osteoporosis. The purpose of this review is to analyze the results of studies of levels of peak bone mass in general, the age of its onset, as well as factors influencing its formation. Factors such as hormonal levels, body composition, physical activity, nutrition, heredity, smoking, lifestyle, prenatal predictors, intestinal microbiota, and vitamin and micronutrient status were considered, and a comprehensive scheme of the influence of these factors on the level of peak bone mass was created. Determining the standards and timing of the formation of peak bone mass, and the factors affecting it, will help in the development of measures to prevent its shortage and the consequent prevention of osteoporosis and concomitant diseases.
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spelling pubmed-106690902023-11-06 Peak Bone Mass Formation: Modern View of the Problem Akhiiarova, Karina Khusainova, Rita Minniakhmetov, Ildar Mokrysheva, Natalia Tyurin, Anton Biomedicines Review Peak bone mass is the amount of bone tissue that is formed when a stable skeletal state is achieved at a young age. To date, there are no established peak bone mass standards nor clear data on the age at which peak bone mass occurs. At the same time, the level of peak bone mass at a young age is an important predictor of the onset of primary osteoporosis. The purpose of this review is to analyze the results of studies of levels of peak bone mass in general, the age of its onset, as well as factors influencing its formation. Factors such as hormonal levels, body composition, physical activity, nutrition, heredity, smoking, lifestyle, prenatal predictors, intestinal microbiota, and vitamin and micronutrient status were considered, and a comprehensive scheme of the influence of these factors on the level of peak bone mass was created. Determining the standards and timing of the formation of peak bone mass, and the factors affecting it, will help in the development of measures to prevent its shortage and the consequent prevention of osteoporosis and concomitant diseases. MDPI 2023-11-06 /pmc/articles/PMC10669090/ /pubmed/38001982 http://dx.doi.org/10.3390/biomedicines11112982 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Akhiiarova, Karina
Khusainova, Rita
Minniakhmetov, Ildar
Mokrysheva, Natalia
Tyurin, Anton
Peak Bone Mass Formation: Modern View of the Problem
title Peak Bone Mass Formation: Modern View of the Problem
title_full Peak Bone Mass Formation: Modern View of the Problem
title_fullStr Peak Bone Mass Formation: Modern View of the Problem
title_full_unstemmed Peak Bone Mass Formation: Modern View of the Problem
title_short Peak Bone Mass Formation: Modern View of the Problem
title_sort peak bone mass formation: modern view of the problem
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669090/
https://www.ncbi.nlm.nih.gov/pubmed/38001982
http://dx.doi.org/10.3390/biomedicines11112982
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