Cargando…

Overexpression of MicroRNA-138 Affects the Proliferation and Invasion of Urothelial Carcinoma Cells by Suppressing SOX9 Expression

SRY-box transcription factor 9 (SOX9) is important for sexual differentiation, chondrogenic differentiation, and cell proliferation in cancer. It acts as a target molecule of microRNA (miR)-138 in various tumors and is associated with tumor development and growth. In this study, we analyzed the func...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nitta, Yuji, Fujii, Tomomi, Uchiyama, Tomoko, Sugimoto, Aya, Nishikawa, Takeshi, Takeda, Maiko, Miyake, Makito, Shimada, Keiji, Fujimoto, Kiyohide
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669193/ https://www.ncbi.nlm.nih.gov/pubmed/38002064 http://dx.doi.org/10.3390/biomedicines11113064

Ejemplares similares

NACC1, as a Target of MicroRNA-331-3p, Regulates Cell Proliferation in Urothelial Carcinoma Cells
por: Morita, Kohei, et al.
Publicado: (2018)

ROS generation via NOX4 and its utility in the cytological diagnosis of urothelial carcinoma of the urinary bladder
por: Shimada, Keiji, et al.
Publicado: (2011)

Emerging biomarkers for the diagnosis and monitoring of urothelial carcinoma
por: Miyake, Makito, et al.
Publicado: (2018)

microRNA-145 promotes differentiation in human urothelial carcinoma through down-regulation of syndecan-1
por: Fujii, Tomomi, et al.
Publicado: (2015)

Colony-stimulating factors detected in tumor cells and voided urine are potential prognostic markers for patients with muscle-invasive bladder cancer undergoing radical cystectomy
por: Morizawa, Yosuke, et al.
Publicado: (2018)

Efficacy of pembrolizumab rechallenge for metastatic urothelial carcinoma
por: Nishimura, Nobutaka, et al.
Publicado: (2022)

Response of Patients with Taxane-Refractory Advanced Urothelial Cancer to Enfortumab Vedotin, a Microtubule-Disrupting Agent
por: Miyake, Makito, et al.
Publicado: (2023)

Inhibition of Heparanase Expression Results in Suppression of Invasion, Migration and Adhesion Abilities of Bladder Cancer Cells
por: Tatsumi, Yoshihiro, et al.
Publicado: (2020)

Disabled Homolog 2 (DAB2) Protein in Tumor Microenvironment Correlates with Aggressive Phenotype in Human Urothelial Carcinoma of the Bladder
por: Itami, Yoshitaka, et al.
Publicado: (2020)

Review by urological pathologists improves the accuracy of Gleason grading by general pathologists
por: Nakai, Yasushi, et al.
Publicado: (2015)

Prostate diseases and microbiome in the prostate, gut, and urine
por: Miyake, Makito, et al.
Publicado: (2022)

Clinical impact of postoperative loss in psoas major muscle and nutrition index after radical cystectomy for patients with urothelial carcinoma of the bladder
por: Miyake, Makito, et al.
Publicado: (2017)

Erratum to: Clinical impact of postoperative loss in psoas major muscle and nutrition index after radical cystectomy for patients with urothelial carcinoma of the bladder
por: Miyake, Makito, et al.
Publicado: (2017)

Pretreatment assessment and perioperative nutritional interventions for patients with bladder cancer undergoing radical cystectomy
por: Miyake, Makito, et al.
Publicado: (2018)

Trends in risk classification and primary therapy of Japanese patients with prostate cancer in Nara urological research and treatment group (NURTG) – comparison between 2004–2006, 2007–2009, and 2010–2012
por: Tanaka, Nobumichi, et al.
Publicado: (2017)

Clinical Impact of Tumor-Infiltrating Lymphocytes and PD-L1-Positive Cells as Prognostic and Predictive Biomarkers in Urological Malignancies and Retroperitoneal Sarcoma
por: Miyake, Makito, et al.
Publicado: (2020)

Probiotics enhances anti‐tumor immune response induced by gemcitabine plus cisplatin chemotherapy for urothelial cancer
por: Miyake, Makito, et al.
Publicado: (2022)

Active surveillance for nonmuscle invasive bladder cancer
por: Miyake, Makito, et al.
Publicado: (2016)

Atypical small acinar proliferation and two or more cores of high-grade intraepithelial neoplasia on a previous prostate biopsy are significant predictors of cancer during a transperineal template-guided saturation biopsy aimed at sampling one core for each 1 mL of prostate volume
por: Nakai, Yasushi, et al.
Publicado: (2017)

Comparison of PSA value at last follow-up of patients who underwent low-dose rate brachytherapy and intensity-modulated radiation therapy for prostate cancer
por: Tanaka, Nobumichi, et al.
Publicado: (2017)

Analysis of quality of life after randomized controlled trial of alpha-1 adrenoceptor antagonist alone and in combination with cyclooxygenase-2 inhibitor in patients who underwent low-dose-rate brachytherapy for prostate cancer
por: Nakai, Yasushi, et al.
Publicado: (2019)

Effect of Prolonged Duration of Transrectal Ultrasound-Guided Biopsy of the Prostate and Pre-Procedure Anxiety on Pain in Patients without Anesthesia
por: Nakai, Yasushi, et al.
Publicado: (2021)

Extended resection including adjacent organs and Ki-67 labeling index are prognostic factors in patients with retroperitoneal soft tissue sarcomas
por: Morizawa, Yosuke, et al.
Publicado: (2016)

The optimal number of initial prostate biopsy cores in daily practice: a prospective study using the Nara Urological Research and Treatment Group nomogram
por: Tanaka, Nobumichi, et al.
Publicado: (2015)

Site-specific Risk Stratification Models for Postoperative Recurrence and Survival Prediction in Patients with Upper Tract Urothelial Carcinoma Undergoing Radical Nephroureterectomy: Better Stratification for Adjuvant Therapy
por: Miyake, Makito, et al.
Publicado: (2022)

Transperineal template-guided saturation biopsy aimed at sampling one core for each milliliter of prostate volume: 103 cases requiring repeat prostate biopsy
por: Nakai, Yasushi, et al.
Publicado: (2017)

Diffuse large B-cell lymphoma (DLBCL) with significant intravascular invasion. Close resemblance of its clinicopathological features to intravascular large B-cell lymphoma, but not to DLBCL-not otherwise specified
por: Itami, Hiroe, et al.
Publicado: (2021)

Additional oncological benefit of photodynamic diagnosis with blue light cystoscopy in transurethral resection for primary non‐muscle‐invasive bladder cancer: A comparative study from experienced institutes
por: Miyake, Makito, et al.
Publicado: (2023)

Molecular Analysis of Liquid-Based Cytological Specimen Using Virtually Positive Sputum with Adenocarcinoma Cells
por: Nishikawa, Takeshi, et al.
Publicado: (2020)

Clinical Impact of Sarcopenia and Inflammatory/Nutritional Markers in Patients with Unresectable Metastatic Urothelial Carcinoma Treated with Pembrolizumab
por: Shimizu, Takuto, et al.
Publicado: (2020)

Quality of life in patients who underwent (125)I brachytherapy, (125)I brachytherapy combined with three-dimensional conformal radiation therapy, or intensity-modulated radiation therapy, for prostate cancer
por: Nakai, Yasushi, et al.
Publicado: (2019)

Quality of life worsened the most severely in patients immediately after intensity-modulated radiotherapy for prostate cancer
por: Nakai, Yasushi, et al.
Publicado: (2018)

Depth of invasion to the bladder wall as a prognostic factor and its association with circulating cell-free DNA levels in patients with muscle-invasive bladder cancer
por: Iemura, Yusuke, et al.
Publicado: (2023)

A Potential Application of Dynamic Contrast-Enhanced Magnetic Resonance Imaging Combined with Photodynamic Diagnosis for the Detection of Bladder Carcinoma in Situ: Toward the Future ‘MRI-PDD Fusion TURBT’
por: Miyake, Makito, et al.
Publicado: (2019)

Risk stratification by means of biological age-related factors better predicts cancer-specific survival than chronological age in patients with upper tract urothelial carcinoma: a multi-institutional database study
por: Inamoto, Teruo, et al.
Publicado: (2018)

Comparison of cancer detection rates by transrectal prostate biopsy for prostate cancer using two different nomograms based on patient’s age and prostate volume
por: Hori, Shunta, et al.
Publicado: (2019)

Changes in lower urinary tract symptoms after iodine-125 brachytherapy for prostate cancer
por: Onishi, Kenta, et al.
Publicado: (2018)

Phenotypic characterization of adenomyosis occurring at the inner and outer myometrium
por: Kishi, Yohei, et al.
Publicado: (2017)

miR-138 inhibits gastric cancer growth by suppressing SOX4
por: Pang, Lei, et al.
Publicado: (2022)

Response to flutamide, as second-line therapy after bicalutamide, predicts efficacy of abiraterone, not that of enzalutamide
por: Nakai, Yasushi, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_1mfk0l8iu1uv3hdr8sbae7pkkg