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Enrichment of Deleterious Mutated Genes Involved in Ciliary Function and Histone Modification in Brain Cancer Patient-Derived Xenograft Models

Patient-derived xenograft (PDX) models, which can retain the characteristics of original tumors in an in vivo-mimicking environment, have been developed to identify better treatment options. However, although original tumors and xenograft tissues mostly share oncogenic mutations and global gene expr...

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Detalles Bibliográficos
Autores principales: Jeong, Hyeongsun, Moon, Hyo Eun, Yun, Seongmin, Cho, Seung Woo, Park, Hye Ran, Park, Sung-Hye, Myung, Kyungjae, Kwon, Taejoon, Paek, Sun Ha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669283/
https://www.ncbi.nlm.nih.gov/pubmed/38001935
http://dx.doi.org/10.3390/biomedicines11112934