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Enhanced Pelican Optimization Algorithm with Deep Learning-Driven Mitotic Nuclei Classification on Breast Histopathology Images

Breast cancer (BC) is a prevalent disease worldwide, and accurate diagnoses are vital for successful treatment. Histopathological (HI) inspection, particularly the detection of mitotic nuclei, has played a pivotal function in the prognosis and diagnosis of BC. It includes the detection and classific...

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Autores principales: Alrowais, Fadwa, Alotaibi, Faiz Abdullah, Hassan, Abdulkhaleq Q. A., Marzouk, Radwa, Alnfiai, Mrim M., Sayed, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669319/
https://www.ncbi.nlm.nih.gov/pubmed/37999179
http://dx.doi.org/10.3390/biomimetics8070538
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author Alrowais, Fadwa
Alotaibi, Faiz Abdullah
Hassan, Abdulkhaleq Q. A.
Marzouk, Radwa
Alnfiai, Mrim M.
Sayed, Ahmed
author_facet Alrowais, Fadwa
Alotaibi, Faiz Abdullah
Hassan, Abdulkhaleq Q. A.
Marzouk, Radwa
Alnfiai, Mrim M.
Sayed, Ahmed
author_sort Alrowais, Fadwa
collection PubMed
description Breast cancer (BC) is a prevalent disease worldwide, and accurate diagnoses are vital for successful treatment. Histopathological (HI) inspection, particularly the detection of mitotic nuclei, has played a pivotal function in the prognosis and diagnosis of BC. It includes the detection and classification of mitotic nuclei within breast tissue samples. Conventionally, the detection of mitotic nuclei has been a subjective task and is time-consuming for pathologists to perform manually. Automatic classification using computer algorithms, especially deep learning (DL) algorithms, has been developed as a beneficial alternative. DL and CNNs particularly have shown outstanding performance in different image classification tasks, including mitotic nuclei classification. CNNs can learn intricate hierarchical features from HI images, making them suitable for detecting subtle patterns related to the mitotic nuclei. In this article, we present an Enhanced Pelican Optimization Algorithm with a Deep Learning-Driven Mitotic Nuclei Classification (EPOADL-MNC) technique on Breast HI. This developed EPOADL-MNC system examines the histopathology images for the classification of mitotic and non-mitotic cells. In this presented EPOADL-MNC technique, the ShuffleNet model can be employed for the feature extraction method. In the hyperparameter tuning procedure, the EPOADL-MNC algorithm makes use of the EPOA system to alter the hyperparameters of the ShuffleNet model. Finally, we used an adaptive neuro-fuzzy inference system (ANFIS) for the classification and detection of mitotic cell nuclei on histopathology images. A series of simulations took place to validate the improved detection performance of the EPOADL-MNC technique. The comprehensive outcomes highlighted the better outcomes of the EPOADL-MNC algorithm compared to existing DL techniques with a maximum accuracy of 97.83%.
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spelling pubmed-106693192023-11-10 Enhanced Pelican Optimization Algorithm with Deep Learning-Driven Mitotic Nuclei Classification on Breast Histopathology Images Alrowais, Fadwa Alotaibi, Faiz Abdullah Hassan, Abdulkhaleq Q. A. Marzouk, Radwa Alnfiai, Mrim M. Sayed, Ahmed Biomimetics (Basel) Article Breast cancer (BC) is a prevalent disease worldwide, and accurate diagnoses are vital for successful treatment. Histopathological (HI) inspection, particularly the detection of mitotic nuclei, has played a pivotal function in the prognosis and diagnosis of BC. It includes the detection and classification of mitotic nuclei within breast tissue samples. Conventionally, the detection of mitotic nuclei has been a subjective task and is time-consuming for pathologists to perform manually. Automatic classification using computer algorithms, especially deep learning (DL) algorithms, has been developed as a beneficial alternative. DL and CNNs particularly have shown outstanding performance in different image classification tasks, including mitotic nuclei classification. CNNs can learn intricate hierarchical features from HI images, making them suitable for detecting subtle patterns related to the mitotic nuclei. In this article, we present an Enhanced Pelican Optimization Algorithm with a Deep Learning-Driven Mitotic Nuclei Classification (EPOADL-MNC) technique on Breast HI. This developed EPOADL-MNC system examines the histopathology images for the classification of mitotic and non-mitotic cells. In this presented EPOADL-MNC technique, the ShuffleNet model can be employed for the feature extraction method. In the hyperparameter tuning procedure, the EPOADL-MNC algorithm makes use of the EPOA system to alter the hyperparameters of the ShuffleNet model. Finally, we used an adaptive neuro-fuzzy inference system (ANFIS) for the classification and detection of mitotic cell nuclei on histopathology images. A series of simulations took place to validate the improved detection performance of the EPOADL-MNC technique. The comprehensive outcomes highlighted the better outcomes of the EPOADL-MNC algorithm compared to existing DL techniques with a maximum accuracy of 97.83%. MDPI 2023-11-10 /pmc/articles/PMC10669319/ /pubmed/37999179 http://dx.doi.org/10.3390/biomimetics8070538 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Alrowais, Fadwa
Alotaibi, Faiz Abdullah
Hassan, Abdulkhaleq Q. A.
Marzouk, Radwa
Alnfiai, Mrim M.
Sayed, Ahmed
Enhanced Pelican Optimization Algorithm with Deep Learning-Driven Mitotic Nuclei Classification on Breast Histopathology Images
title Enhanced Pelican Optimization Algorithm with Deep Learning-Driven Mitotic Nuclei Classification on Breast Histopathology Images
title_full Enhanced Pelican Optimization Algorithm with Deep Learning-Driven Mitotic Nuclei Classification on Breast Histopathology Images
title_fullStr Enhanced Pelican Optimization Algorithm with Deep Learning-Driven Mitotic Nuclei Classification on Breast Histopathology Images
title_full_unstemmed Enhanced Pelican Optimization Algorithm with Deep Learning-Driven Mitotic Nuclei Classification on Breast Histopathology Images
title_short Enhanced Pelican Optimization Algorithm with Deep Learning-Driven Mitotic Nuclei Classification on Breast Histopathology Images
title_sort enhanced pelican optimization algorithm with deep learning-driven mitotic nuclei classification on breast histopathology images
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669319/
https://www.ncbi.nlm.nih.gov/pubmed/37999179
http://dx.doi.org/10.3390/biomimetics8070538
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