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Towards a Corpus (and Language)-Independent Screening of Parkinson’s Disease from Voice and Speech through Domain Adaptation

End-to-end deep learning models have shown promising results for the automatic screening of Parkinson’s disease by voice and speech. However, these models often suffer degradation in their performance when applied to scenarios involving multiple corpora. In addition, they also show corpus-dependent...

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Autores principales: Ibarra, Emiro J., Arias-Londoño, Julián D., Zañartu, Matías, Godino-Llorente, Juan I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669342/
https://www.ncbi.nlm.nih.gov/pubmed/38002440
http://dx.doi.org/10.3390/bioengineering10111316
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author Ibarra, Emiro J.
Arias-Londoño, Julián D.
Zañartu, Matías
Godino-Llorente, Juan I.
author_facet Ibarra, Emiro J.
Arias-Londoño, Julián D.
Zañartu, Matías
Godino-Llorente, Juan I.
author_sort Ibarra, Emiro J.
collection PubMed
description End-to-end deep learning models have shown promising results for the automatic screening of Parkinson’s disease by voice and speech. However, these models often suffer degradation in their performance when applied to scenarios involving multiple corpora. In addition, they also show corpus-dependent clusterings. These facts indicate a lack of generalisation or the presence of certain shortcuts in the decision, and also suggest the need for developing new corpus-independent models. In this respect, this work explores the use of domain adversarial training as a viable strategy to develop models that retain their discriminative capacity to detect Parkinson’s disease across diverse datasets. The paper presents three deep learning architectures and their domain adversarial counterparts. The models were evaluated with sustained vowels and diadochokinetic recordings extracted from four corpora with different demographics, dialects or languages, and recording conditions. The results showed that the space distribution of the embedding features extracted by the domain adversarial networks exhibits a higher intra-class cohesion. This behaviour is supported by a decrease in the variability and inter-domain divergence computed within each class. The findings suggest that domain adversarial networks are able to learn the common characteristics present in Parkinsonian voice and speech, which are supposed to be corpus, and consequently, language independent. Overall, this effort provides evidence that domain adaptation techniques refine the existing end-to-end deep learning approaches for Parkinson’s disease detection from voice and speech, achieving more generalizable models.
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spelling pubmed-106693422023-11-15 Towards a Corpus (and Language)-Independent Screening of Parkinson’s Disease from Voice and Speech through Domain Adaptation Ibarra, Emiro J. Arias-Londoño, Julián D. Zañartu, Matías Godino-Llorente, Juan I. Bioengineering (Basel) Article End-to-end deep learning models have shown promising results for the automatic screening of Parkinson’s disease by voice and speech. However, these models often suffer degradation in their performance when applied to scenarios involving multiple corpora. In addition, they also show corpus-dependent clusterings. These facts indicate a lack of generalisation or the presence of certain shortcuts in the decision, and also suggest the need for developing new corpus-independent models. In this respect, this work explores the use of domain adversarial training as a viable strategy to develop models that retain their discriminative capacity to detect Parkinson’s disease across diverse datasets. The paper presents three deep learning architectures and their domain adversarial counterparts. The models were evaluated with sustained vowels and diadochokinetic recordings extracted from four corpora with different demographics, dialects or languages, and recording conditions. The results showed that the space distribution of the embedding features extracted by the domain adversarial networks exhibits a higher intra-class cohesion. This behaviour is supported by a decrease in the variability and inter-domain divergence computed within each class. The findings suggest that domain adversarial networks are able to learn the common characteristics present in Parkinsonian voice and speech, which are supposed to be corpus, and consequently, language independent. Overall, this effort provides evidence that domain adaptation techniques refine the existing end-to-end deep learning approaches for Parkinson’s disease detection from voice and speech, achieving more generalizable models. MDPI 2023-11-15 /pmc/articles/PMC10669342/ /pubmed/38002440 http://dx.doi.org/10.3390/bioengineering10111316 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ibarra, Emiro J.
Arias-Londoño, Julián D.
Zañartu, Matías
Godino-Llorente, Juan I.
Towards a Corpus (and Language)-Independent Screening of Parkinson’s Disease from Voice and Speech through Domain Adaptation
title Towards a Corpus (and Language)-Independent Screening of Parkinson’s Disease from Voice and Speech through Domain Adaptation
title_full Towards a Corpus (and Language)-Independent Screening of Parkinson’s Disease from Voice and Speech through Domain Adaptation
title_fullStr Towards a Corpus (and Language)-Independent Screening of Parkinson’s Disease from Voice and Speech through Domain Adaptation
title_full_unstemmed Towards a Corpus (and Language)-Independent Screening of Parkinson’s Disease from Voice and Speech through Domain Adaptation
title_short Towards a Corpus (and Language)-Independent Screening of Parkinson’s Disease from Voice and Speech through Domain Adaptation
title_sort towards a corpus (and language)-independent screening of parkinson’s disease from voice and speech through domain adaptation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669342/
https://www.ncbi.nlm.nih.gov/pubmed/38002440
http://dx.doi.org/10.3390/bioengineering10111316
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