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Portable Infrared-Based Glucometer Reinforced with Fuzzy Logic

Diabetes mellitus (DM) is a chronic metabolic condition characterized by high blood glucose levels owing to decreased insulin production or sensitivity. Current diagnostic approaches for gestational diabetes entail intrusive blood tests, which are painful and impractical for regular monitoring. Addi...

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Autores principales: Nazha, Hasan Mhd, Darwich, Mhd Ayham, Ismaiel, Ebrahim, Shahen, Anas, Nasser, Tamim, Assaad, Maher, Juhre, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669386/
https://www.ncbi.nlm.nih.gov/pubmed/37998166
http://dx.doi.org/10.3390/bios13110991
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author Nazha, Hasan Mhd
Darwich, Mhd Ayham
Ismaiel, Ebrahim
Shahen, Anas
Nasser, Tamim
Assaad, Maher
Juhre, Daniel
author_facet Nazha, Hasan Mhd
Darwich, Mhd Ayham
Ismaiel, Ebrahim
Shahen, Anas
Nasser, Tamim
Assaad, Maher
Juhre, Daniel
author_sort Nazha, Hasan Mhd
collection PubMed
description Diabetes mellitus (DM) is a chronic metabolic condition characterized by high blood glucose levels owing to decreased insulin production or sensitivity. Current diagnostic approaches for gestational diabetes entail intrusive blood tests, which are painful and impractical for regular monitoring. Additionally, typical blood glucose monitoring systems are restricted in their measurement frequency and need finger pricks for blood samples. This research study focuses on the development of a non-invasive, real-time glucose monitoring method based on the detection of glucose in human tears and finger blood using mid-infrared (IR) spectroscopy. The proposed solution combines a fuzzy logic-based calibration mechanism with an IR sensor and Arduino controller. This calibration technique increases the accuracy of non-invasive glucose testing based on MID absorbance in fingertips and human tears. The data demonstrate that our device has high accuracy and reliability, with an error rate of less than 3%, according to the EGA. Out of 360 measurements, 97.5% fell into zone A, 2.2% into zone B, and 0.3% into zone C of the Clarke Error Grid. This suggests that our device can give clinically precise and acceptable estimates of blood glucose levels without inflicting any harm or discomfort on the user.
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spelling pubmed-106693862023-11-20 Portable Infrared-Based Glucometer Reinforced with Fuzzy Logic Nazha, Hasan Mhd Darwich, Mhd Ayham Ismaiel, Ebrahim Shahen, Anas Nasser, Tamim Assaad, Maher Juhre, Daniel Biosensors (Basel) Article Diabetes mellitus (DM) is a chronic metabolic condition characterized by high blood glucose levels owing to decreased insulin production or sensitivity. Current diagnostic approaches for gestational diabetes entail intrusive blood tests, which are painful and impractical for regular monitoring. Additionally, typical blood glucose monitoring systems are restricted in their measurement frequency and need finger pricks for blood samples. This research study focuses on the development of a non-invasive, real-time glucose monitoring method based on the detection of glucose in human tears and finger blood using mid-infrared (IR) spectroscopy. The proposed solution combines a fuzzy logic-based calibration mechanism with an IR sensor and Arduino controller. This calibration technique increases the accuracy of non-invasive glucose testing based on MID absorbance in fingertips and human tears. The data demonstrate that our device has high accuracy and reliability, with an error rate of less than 3%, according to the EGA. Out of 360 measurements, 97.5% fell into zone A, 2.2% into zone B, and 0.3% into zone C of the Clarke Error Grid. This suggests that our device can give clinically precise and acceptable estimates of blood glucose levels without inflicting any harm or discomfort on the user. MDPI 2023-11-20 /pmc/articles/PMC10669386/ /pubmed/37998166 http://dx.doi.org/10.3390/bios13110991 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Nazha, Hasan Mhd
Darwich, Mhd Ayham
Ismaiel, Ebrahim
Shahen, Anas
Nasser, Tamim
Assaad, Maher
Juhre, Daniel
Portable Infrared-Based Glucometer Reinforced with Fuzzy Logic
title Portable Infrared-Based Glucometer Reinforced with Fuzzy Logic
title_full Portable Infrared-Based Glucometer Reinforced with Fuzzy Logic
title_fullStr Portable Infrared-Based Glucometer Reinforced with Fuzzy Logic
title_full_unstemmed Portable Infrared-Based Glucometer Reinforced with Fuzzy Logic
title_short Portable Infrared-Based Glucometer Reinforced with Fuzzy Logic
title_sort portable infrared-based glucometer reinforced with fuzzy logic
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669386/
https://www.ncbi.nlm.nih.gov/pubmed/37998166
http://dx.doi.org/10.3390/bios13110991
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