Cargando…

Chalcogen-Varied Imidazolone Derivatives as Antibiotic Resistance Breakers in Staphylococcus aureus Strains

In this study, a search for new therapeutic agents that may improve the antibacterial activity of conventional antibiotics and help to successfully overcome methicillin-resistant Staphylococcus aureus (MRSA) infections has been conducted. The purpose of this work was to extend the scope of our preli...

Descripción completa

Detalles Bibliográficos
Autores principales:	Witek, Karolina, Kaczor, Aneta, Żesławska, Ewa, Podlewska, Sabina, Marć, Małgorzata Anna, Czarnota-Łydka, Kinga, Nitek, Wojciech, Latacz, Gniewomir, Tejchman, Waldemar, Bischoff, Markus, Jacob, Claus, Handzlik, Jadwiga
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669504/ https://www.ncbi.nlm.nih.gov/pubmed/37998820 http://dx.doi.org/10.3390/antibiotics12111618

Ejemplares similares

5-Arylideneimidazolones with Amine at Position 3 as Potential Antibiotic Adjuvants against Multidrug Resistant Bacteria
por: Kaczor, Aneta, et al.
Publicado: (2019)

Phenylpiperazine 5,5-Dimethylhydantoin Derivatives as First Synthetic Inhibitors of Msr(A) Efflux Pump in Staphylococcus epidermidis
por: Witek, Karolina, et al.
Publicado: (2020)

Molecular Insights into an Antibiotic Enhancer Action of New Morpholine-Containing 5-Arylideneimidazolones in the Fight against MDR Bacteria
por: Kaczor, Aneta, et al.
Publicado: (2021)

Multitargeting the Action of 5-HT(6) Serotonin Receptor Ligands by Additional Modulation of Kinases in the Search for a New Therapy for Alzheimer’s Disease: Can It Work from a Molecular Point of View?
por: Czarnota-Łydka, Kinga, et al.
Publicado: (2022)

Highly efficient microwave synthesis of rhodanine and 2-thiohydantoin derivatives and determination of relationships between their chemical structures and antibacterial activity
por: Tejchman, Waldemar, et al.
Publicado: (2019)

New Triazine Derivatives as Serotonin 5-HT(6) Receptor Ligands
por: Łażewska, Dorota, et al.
Publicado: (2023)

Search for ABCB1 Modulators Among 2-Amine-5-Arylideneimidazolones as a New Perspective to Overcome Cancer Multidrug Resistance
por: Kaczor, Aneta, et al.
Publicado: (2020)

5-Arylidenerhodanines as P-gp Modulators: An Interesting Effect of the Carboxyl Group on ABCB1 Function in Multidrug-Resistant Cancer Cells
por: Żesławska, Ewa, et al.
Publicado: (2022)

Discovery of Cinnamylidene Derivative of Rhodanine with High Anthelmintic Activity against Rhabditis sp.
por: Tejchman, Waldemar, et al.
Publicado: (2022)

The Structural Determinants for α(1)-Adrenergic/Serotonin Receptors Activity among Phenylpiperazine-Hydantoin Derivatives
por: Kucwaj-Brysz, Katarzyna, et al.
Publicado: (2021)

Antibacterial properties of 5-substituted derivatives of rhodanine-3-carboxyalkyl acids. Part II
por: Tejchman, Waldemar, et al.
Publicado: (2020)

Selenazolinium Salts as “Small Molecule Catalysts” with High Potency against ESKAPE Bacterial Pathogens
por: Witek, Karolina, et al.
Publicado: (2017)

[3+2]-Cycloaddition of azomethine ylides to 5-methylidene-3-aryl-2-сhalcogen-imidazolones: access to dispiro indolinone-pyrrolidine-imidazolones
por: Kukushkin, Maxim E., et al.
Publicado: (2022)

Pharmaceutical and Safety Profile Evaluation of Novel Selenocompounds with Noteworthy Anticancer Activity
por: Marć, Małgorzata Anna, et al.
Publicado: (2022)

Aspects of a Distinct Cytotoxicity of Selenium Salts and Organic Selenides in Living Cells with Possible Implications for Drug Design
por: Castellucci Estevam, Ethiene, et al.
Publicado: (2015)

Low Basicity as a Characteristic for Atypical Ligands of Serotonin Receptor 5-HT2
por: Podlewska, Sabina, et al.
Publicado: (2021)

Novel N-Substituted 3-Aryl-4-(diethoxyphosphoryl)azetidin-2-ones as Antibiotic Enhancers and Antiviral Agents in Search for a Successful Treatment of Complex Infections
por: Głowacka, Iwona E., et al.
Publicado: (2021)

The Record Breakers
por: Peplow, Mark
Publicado: (2016)

Breakers Ahead
Publicado: (1892)

Breaker of chains
por: Davies, Kevin
Publicado: (2021)

Chalcone-imidazolone conjugates induce apoptosis through DNA damage pathway by affecting telomeres
por: Ramaiah, M Janaki, et al.
Publicado: (2011)

string's circuit breaker
por: Valeriane Duvivier
Publicado: (2001)

The Mystique of Late Breakers
por: DeMaria, Anthony
Publicado: (2022)

Studies on Anticonvulsant Effects of Novel Histamine H3R Antagonists in Electrically and Chemically Induced Seizures in Rats
por: Alachkar, Alaa, et al.
Publicado: (2018)

2-{5-[(Z,2Z)-2-Chloro-3-(4-nitrophenyl)-2-propenylidene]-4-oxo-2-thioxothiazolidin-3-yl}-3-methylbutanoic Acid as a Potential Anti-Breast Cancer Molecule
por: Buzun, Kamila, et al.
Publicado: (2022)

The Nature of Strong Chalcogen Bonds Involving Chalcogen‐Containing Heterocycles
por: Haberhauer, Gebhard, et al.
Publicado: (2020)

Ultra-fast circuit breaker
por: CERN. Geneva. Super Proton Synchrotron Division (SPS)
Publicado: (1974)

Drugs and the Young Law Breaker
por: Gibbens, T. C. N.
Publicado: (1966)

This Is How To Be a Rule Breaker
por: Wirth, Robert, et al.
Publicado: (2018)

Design, Synthesis and in Vivo Anti-inflammatory Activities of 2,4-Diaryl-5-4H-imidazolone Derivatives
por: El-Araby, Moustafa, et al.
Publicado: (2012)

Treatment of Silylene–Phosphinidene with Chalcogens Resulted Exclusively in the Formation of Silicon‐Bonded Chalcogens
por: Sinhababu, Soumen, et al.
Publicado: (2019)

Histamine H(3) Receptor Ligands—KSK-59 and KSK-73—Reduce Body Weight Gain in a Rat Model of Excessive Eating
por: Mika, Kamil, et al.
Publicado: (2021)

Selectively improving nikkomycin Z production by blocking the imidazolone biosynthetic pathway of nikkomycin X and uracil feeding in Streptomyces ansochromogenes
por: Liao, Guojian, et al.
Publicado: (2009)

Protein Modification with Ribose Generates N(δ)-(5-hydro-5-methyl-4-imidazolone-2-yl)-ornithine
por: Ban, Ikuho, et al.
Publicado: (2022)

Chalcogen-doped, (seco)-hexabenzocoronene-based nanographenes: synthesis, properties, and chalcogen extrusion conversion
por: Li, Ranran, et al.
Publicado: (2023)

The Stereoselectivity and Hydrolysis Efficiency of Recombinant d-Hydantoinase from Vigna angularis Against 5-Benzylhydantoin Derivatives with Halogen and Methyl Substituents
por: Latacz, Gniewomir, et al.
Publicado: (2014)

Statins: antimicrobial resistance breakers or makers?
por: Ko, Humphrey H.T., et al.
Publicado: (2017)

ESCAIDE 2018 – call for late breakers
Publicado: (2018)

COVID-19: a prison-breaker?
por: Dutheil, Frédéric, et al.
Publicado: (2020)

Withdrawn as Duplicate: Late Breaker Abstracts
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_pkl03m1g73h1kvh0aeiig1ucem