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Inhibition of Indoxyl Sulfate-Induced Reactive Oxygen Species-Related Ferroptosis Alleviates Renal Cell Injury In Vitro and Chronic Kidney Disease Progression In Vivo

The accumulation of the uremic toxin indoxyl sulfate (IS) is a key pathological feature of chronic kidney disease (CKD). The effect of IS on ferroptosis and the role of IS-related ferroptosis in CKD are not well understood. We used a renal tubular cell model and an adenine-induced CKD mouse model to...

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Detalles Bibliográficos
Autores principales:	Tsai, Li-Ting, Weng, Te-I, Chang, Ting-Yu, Lan, Kuo-Cheng, Chiang, Chih-Kang, Liu, Shing-Hwa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669521/ https://www.ncbi.nlm.nih.gov/pubmed/38001784 http://dx.doi.org/10.3390/antiox12111931

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