From Stress to Sick(le) and Back Again–Oxidative/Antioxidant Mechanisms, Genetic Modulation, and Cerebrovascular Disease in Children with Sickle Cell Anemia

Sickle cell anemia (SCA) is a genetic disease caused by the homozygosity of the HBB:c.20A>T mutation, which results in the production of hemoglobin S (HbS). In hypoxic conditions, HbS suffers autoxidation and polymerizes inside red blood cells, altering their morphology into a sickle shape, with...

Descripción completa

Detalles Bibliográficos
Autores principales: Silva, Marisa, Faustino, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669666/
https://www.ncbi.nlm.nih.gov/pubmed/38001830
http://dx.doi.org/10.3390/antiox12111977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669666/
https://www.ncbi.nlm.nih.gov/pubmed/38001830
http://dx.doi.org/10.3390/antiox12111977

Ejemplares similares