Targeting the Structural Maturation Pathway of HIV-1 Reverse Transcriptase

Formation of active HIV-1 reverse transcriptase (RT) proceeds via a structural maturation process that involves subdomain rearrangements and formation of an asymmetric p66/p66′ homodimer. These studies were undertaken to evaluate whether the information about this maturation process can be used to i...

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Detalles Bibliográficos
Autores principales: Kirby, Thomas W., Gabel, Scott A., DeRose, Eugene F., Perera, Lalith, Krahn, Juno M., Pedersen, Lars C., London, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669680/
https://www.ncbi.nlm.nih.gov/pubmed/38002285
http://dx.doi.org/10.3390/biom13111603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669680/
https://www.ncbi.nlm.nih.gov/pubmed/38002285
http://dx.doi.org/10.3390/biom13111603

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