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The Efficacy of Cognitive Training on Neuropsychological Outcomes in Mild Cognitive Impairment: A Meta-Analysis

Mild cognitive impairment (MCI) or mild neurocognitive disorder is an intermediate stage of cognitive impairment between normal cognitive aging and dementia. Given the absence of effective pharmacological treatments for MCI, increasing numbers of studies are attempting to understand how cognitive tr...

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Autores principales: Raimo, Simona, Cropano, Maria, Gaita, Mariachiara, Maggi, Gianpaolo, Cavallo, Nicola Davide, Roldan-Tapia, Maria Dolores, Santangelo, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669748/
https://www.ncbi.nlm.nih.gov/pubmed/38002471
http://dx.doi.org/10.3390/brainsci13111510
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author Raimo, Simona
Cropano, Maria
Gaita, Mariachiara
Maggi, Gianpaolo
Cavallo, Nicola Davide
Roldan-Tapia, Maria Dolores
Santangelo, Gabriella
author_facet Raimo, Simona
Cropano, Maria
Gaita, Mariachiara
Maggi, Gianpaolo
Cavallo, Nicola Davide
Roldan-Tapia, Maria Dolores
Santangelo, Gabriella
author_sort Raimo, Simona
collection PubMed
description Mild cognitive impairment (MCI) or mild neurocognitive disorder is an intermediate stage of cognitive impairment between normal cognitive aging and dementia. Given the absence of effective pharmacological treatments for MCI, increasing numbers of studies are attempting to understand how cognitive training (CT) could benefit MCI. This meta-analysis aims to update and assess the efficacy of CT on specific neuropsychological test performance (global cognitive functioning, short-term verbal memory, long-term verbal memory, generativity, working memory, and visuospatial abilities) in individuals diagnosed with MCI, as compared to MCI control groups. After searching electronic databases for randomized controlled trials, 31 studies were found including 2496 participants. Results showed that CT significantly improved global cognitive functioning, short-term and long-term verbal memory, generativity, working memory, and visuospatial abilities. However, no significant effects were observed for shifting, abstraction ability/concept formation, processing speed, and language. The mode of CT had a moderating effect on abstraction ability/concept formation. The findings provide specific insights into the cognitive functions influenced by CT and guide the development of tailored interventions for MCI. While CT holds promise, further research is needed to address certain cognitive deficits and assess long-term effects on dementia progression.
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spelling pubmed-106697482023-10-25 The Efficacy of Cognitive Training on Neuropsychological Outcomes in Mild Cognitive Impairment: A Meta-Analysis Raimo, Simona Cropano, Maria Gaita, Mariachiara Maggi, Gianpaolo Cavallo, Nicola Davide Roldan-Tapia, Maria Dolores Santangelo, Gabriella Brain Sci Systematic Review Mild cognitive impairment (MCI) or mild neurocognitive disorder is an intermediate stage of cognitive impairment between normal cognitive aging and dementia. Given the absence of effective pharmacological treatments for MCI, increasing numbers of studies are attempting to understand how cognitive training (CT) could benefit MCI. This meta-analysis aims to update and assess the efficacy of CT on specific neuropsychological test performance (global cognitive functioning, short-term verbal memory, long-term verbal memory, generativity, working memory, and visuospatial abilities) in individuals diagnosed with MCI, as compared to MCI control groups. After searching electronic databases for randomized controlled trials, 31 studies were found including 2496 participants. Results showed that CT significantly improved global cognitive functioning, short-term and long-term verbal memory, generativity, working memory, and visuospatial abilities. However, no significant effects were observed for shifting, abstraction ability/concept formation, processing speed, and language. The mode of CT had a moderating effect on abstraction ability/concept formation. The findings provide specific insights into the cognitive functions influenced by CT and guide the development of tailored interventions for MCI. While CT holds promise, further research is needed to address certain cognitive deficits and assess long-term effects on dementia progression. MDPI 2023-10-25 /pmc/articles/PMC10669748/ /pubmed/38002471 http://dx.doi.org/10.3390/brainsci13111510 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Systematic Review
Raimo, Simona
Cropano, Maria
Gaita, Mariachiara
Maggi, Gianpaolo
Cavallo, Nicola Davide
Roldan-Tapia, Maria Dolores
Santangelo, Gabriella
The Efficacy of Cognitive Training on Neuropsychological Outcomes in Mild Cognitive Impairment: A Meta-Analysis
title The Efficacy of Cognitive Training on Neuropsychological Outcomes in Mild Cognitive Impairment: A Meta-Analysis
title_full The Efficacy of Cognitive Training on Neuropsychological Outcomes in Mild Cognitive Impairment: A Meta-Analysis
title_fullStr The Efficacy of Cognitive Training on Neuropsychological Outcomes in Mild Cognitive Impairment: A Meta-Analysis
title_full_unstemmed The Efficacy of Cognitive Training on Neuropsychological Outcomes in Mild Cognitive Impairment: A Meta-Analysis
title_short The Efficacy of Cognitive Training on Neuropsychological Outcomes in Mild Cognitive Impairment: A Meta-Analysis
title_sort efficacy of cognitive training on neuropsychological outcomes in mild cognitive impairment: a meta-analysis
topic Systematic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669748/
https://www.ncbi.nlm.nih.gov/pubmed/38002471
http://dx.doi.org/10.3390/brainsci13111510
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