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Association between SMAD4 Mutations and GATA6 Expression in Paired Pancreatic Ductal Adenocarcinoma Tumor Specimens: Data from Two Independent Molecularly-Characterized Cohorts

Several molecular biomarkers have been identified to guide induction treatment selection for localized pancreatic ductal adenocarcinoma (PDAC). SMAD4 alterations and low GATA6 expression/modified “Moffitt” basal-like phenotype have each been associated with inferior survival uniquely for patients re...

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Detalles Bibliográficos
Autores principales: Greendyk, Joshua D., Allen, William E., Alexander, H. Richard, Beninato, Toni, Eskander, Mariam F., Grandhi, Miral S., Kennedy, Timothy J., Langan, Russell C., Maggi, Jason C., De, Subhajyoti, Court, Colin M., Ecker, Brett L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669842/
https://www.ncbi.nlm.nih.gov/pubmed/38002058
http://dx.doi.org/10.3390/biomedicines11113058