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Overlapping Stent Treatment for Ruptured Dissecting Aneurysms in Posterior Circulation

Ruptured dissecting aneurysms in posterior intracranial circulation present significant clinical challenges and often cause poor prognoses. Our cohort used overlapping stents as the primary treatment. We analyzed the medical records of 27 patients (18 men/nine women) with ruptured posterior circulat...

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Autores principales: Zhou, Minghui, Wu, Zengbao, Maalim, Ali Abdi, Zeng, Ying, Guo, Xiao, Zhang, Zhenhua, Yuan, Xiaohong, Enos, Zacharia Majaliwa, Shu, Kai, Lei, Ting, Zhu, Mingxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669846/
https://www.ncbi.nlm.nih.gov/pubmed/38002469
http://dx.doi.org/10.3390/brainsci13111507
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author Zhou, Minghui
Wu, Zengbao
Maalim, Ali Abdi
Zeng, Ying
Guo, Xiao
Zhang, Zhenhua
Yuan, Xiaohong
Enos, Zacharia Majaliwa
Shu, Kai
Lei, Ting
Zhu, Mingxin
author_facet Zhou, Minghui
Wu, Zengbao
Maalim, Ali Abdi
Zeng, Ying
Guo, Xiao
Zhang, Zhenhua
Yuan, Xiaohong
Enos, Zacharia Majaliwa
Shu, Kai
Lei, Ting
Zhu, Mingxin
author_sort Zhou, Minghui
collection PubMed
description Ruptured dissecting aneurysms in posterior intracranial circulation present significant clinical challenges and often cause poor prognoses. Our cohort used overlapping stents as the primary treatment. We analyzed the medical records of 27 patients (18 men/nine women) with ruptured posterior circulation dissecting aneurysms (PCDAs). Their average age was 52 years. We selected 11 patients who used Enterprise (EP) and LVIS stents overlappingly and matched them 1:1 with counterparts who received either EP or LVIS stents individually. Overlapping stents was a feasible treatment in all 27 cases. We successfully followed up 26 patients for ≥6 months. Regrettably, one patient died from intracranial hypertension on Day 7 post-procedure. Immediate post-procedure angiographies indicated Raymond grade I, II, and III occlusions of PCDAs in 16 (59.3%), 7 (25.9%), and 4 (14.8%) cases, respectively. At an average follow-up duration of 16.2 months, 25 patients (96.2%) had modified Rankin Scale scores of 0–2, signifying positive outcomes. One patient (3.8%) had a score of 3–4. Recurrence rates for the EP and LVIS stent groups were higher than those of the overlapping stent group (45.45% vs. 9.09%, p = 0.15 and 27.27% vs. 9.09%, p = 0.59, respectively). No significant difference in recurrence rates existed between the overlapping and single-stent groups. Similarly, follow-up outcomes were consistent between the two groups. Overlapping stents could be an efficient method for treating ruptured PCDAs.
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spelling pubmed-106698462023-10-25 Overlapping Stent Treatment for Ruptured Dissecting Aneurysms in Posterior Circulation Zhou, Minghui Wu, Zengbao Maalim, Ali Abdi Zeng, Ying Guo, Xiao Zhang, Zhenhua Yuan, Xiaohong Enos, Zacharia Majaliwa Shu, Kai Lei, Ting Zhu, Mingxin Brain Sci Article Ruptured dissecting aneurysms in posterior intracranial circulation present significant clinical challenges and often cause poor prognoses. Our cohort used overlapping stents as the primary treatment. We analyzed the medical records of 27 patients (18 men/nine women) with ruptured posterior circulation dissecting aneurysms (PCDAs). Their average age was 52 years. We selected 11 patients who used Enterprise (EP) and LVIS stents overlappingly and matched them 1:1 with counterparts who received either EP or LVIS stents individually. Overlapping stents was a feasible treatment in all 27 cases. We successfully followed up 26 patients for ≥6 months. Regrettably, one patient died from intracranial hypertension on Day 7 post-procedure. Immediate post-procedure angiographies indicated Raymond grade I, II, and III occlusions of PCDAs in 16 (59.3%), 7 (25.9%), and 4 (14.8%) cases, respectively. At an average follow-up duration of 16.2 months, 25 patients (96.2%) had modified Rankin Scale scores of 0–2, signifying positive outcomes. One patient (3.8%) had a score of 3–4. Recurrence rates for the EP and LVIS stent groups were higher than those of the overlapping stent group (45.45% vs. 9.09%, p = 0.15 and 27.27% vs. 9.09%, p = 0.59, respectively). No significant difference in recurrence rates existed between the overlapping and single-stent groups. Similarly, follow-up outcomes were consistent between the two groups. Overlapping stents could be an efficient method for treating ruptured PCDAs. MDPI 2023-10-25 /pmc/articles/PMC10669846/ /pubmed/38002469 http://dx.doi.org/10.3390/brainsci13111507 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zhou, Minghui
Wu, Zengbao
Maalim, Ali Abdi
Zeng, Ying
Guo, Xiao
Zhang, Zhenhua
Yuan, Xiaohong
Enos, Zacharia Majaliwa
Shu, Kai
Lei, Ting
Zhu, Mingxin
Overlapping Stent Treatment for Ruptured Dissecting Aneurysms in Posterior Circulation
title Overlapping Stent Treatment for Ruptured Dissecting Aneurysms in Posterior Circulation
title_full Overlapping Stent Treatment for Ruptured Dissecting Aneurysms in Posterior Circulation
title_fullStr Overlapping Stent Treatment for Ruptured Dissecting Aneurysms in Posterior Circulation
title_full_unstemmed Overlapping Stent Treatment for Ruptured Dissecting Aneurysms in Posterior Circulation
title_short Overlapping Stent Treatment for Ruptured Dissecting Aneurysms in Posterior Circulation
title_sort overlapping stent treatment for ruptured dissecting aneurysms in posterior circulation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669846/
https://www.ncbi.nlm.nih.gov/pubmed/38002469
http://dx.doi.org/10.3390/brainsci13111507
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