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Overlapping Stent Treatment for Ruptured Dissecting Aneurysms in Posterior Circulation
Ruptured dissecting aneurysms in posterior intracranial circulation present significant clinical challenges and often cause poor prognoses. Our cohort used overlapping stents as the primary treatment. We analyzed the medical records of 27 patients (18 men/nine women) with ruptured posterior circulat...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669846/ https://www.ncbi.nlm.nih.gov/pubmed/38002469 http://dx.doi.org/10.3390/brainsci13111507 |
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author | Zhou, Minghui Wu, Zengbao Maalim, Ali Abdi Zeng, Ying Guo, Xiao Zhang, Zhenhua Yuan, Xiaohong Enos, Zacharia Majaliwa Shu, Kai Lei, Ting Zhu, Mingxin |
author_facet | Zhou, Minghui Wu, Zengbao Maalim, Ali Abdi Zeng, Ying Guo, Xiao Zhang, Zhenhua Yuan, Xiaohong Enos, Zacharia Majaliwa Shu, Kai Lei, Ting Zhu, Mingxin |
author_sort | Zhou, Minghui |
collection | PubMed |
description | Ruptured dissecting aneurysms in posterior intracranial circulation present significant clinical challenges and often cause poor prognoses. Our cohort used overlapping stents as the primary treatment. We analyzed the medical records of 27 patients (18 men/nine women) with ruptured posterior circulation dissecting aneurysms (PCDAs). Their average age was 52 years. We selected 11 patients who used Enterprise (EP) and LVIS stents overlappingly and matched them 1:1 with counterparts who received either EP or LVIS stents individually. Overlapping stents was a feasible treatment in all 27 cases. We successfully followed up 26 patients for ≥6 months. Regrettably, one patient died from intracranial hypertension on Day 7 post-procedure. Immediate post-procedure angiographies indicated Raymond grade I, II, and III occlusions of PCDAs in 16 (59.3%), 7 (25.9%), and 4 (14.8%) cases, respectively. At an average follow-up duration of 16.2 months, 25 patients (96.2%) had modified Rankin Scale scores of 0–2, signifying positive outcomes. One patient (3.8%) had a score of 3–4. Recurrence rates for the EP and LVIS stent groups were higher than those of the overlapping stent group (45.45% vs. 9.09%, p = 0.15 and 27.27% vs. 9.09%, p = 0.59, respectively). No significant difference in recurrence rates existed between the overlapping and single-stent groups. Similarly, follow-up outcomes were consistent between the two groups. Overlapping stents could be an efficient method for treating ruptured PCDAs. |
format | Online Article Text |
id | pubmed-10669846 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-106698462023-10-25 Overlapping Stent Treatment for Ruptured Dissecting Aneurysms in Posterior Circulation Zhou, Minghui Wu, Zengbao Maalim, Ali Abdi Zeng, Ying Guo, Xiao Zhang, Zhenhua Yuan, Xiaohong Enos, Zacharia Majaliwa Shu, Kai Lei, Ting Zhu, Mingxin Brain Sci Article Ruptured dissecting aneurysms in posterior intracranial circulation present significant clinical challenges and often cause poor prognoses. Our cohort used overlapping stents as the primary treatment. We analyzed the medical records of 27 patients (18 men/nine women) with ruptured posterior circulation dissecting aneurysms (PCDAs). Their average age was 52 years. We selected 11 patients who used Enterprise (EP) and LVIS stents overlappingly and matched them 1:1 with counterparts who received either EP or LVIS stents individually. Overlapping stents was a feasible treatment in all 27 cases. We successfully followed up 26 patients for ≥6 months. Regrettably, one patient died from intracranial hypertension on Day 7 post-procedure. Immediate post-procedure angiographies indicated Raymond grade I, II, and III occlusions of PCDAs in 16 (59.3%), 7 (25.9%), and 4 (14.8%) cases, respectively. At an average follow-up duration of 16.2 months, 25 patients (96.2%) had modified Rankin Scale scores of 0–2, signifying positive outcomes. One patient (3.8%) had a score of 3–4. Recurrence rates for the EP and LVIS stent groups were higher than those of the overlapping stent group (45.45% vs. 9.09%, p = 0.15 and 27.27% vs. 9.09%, p = 0.59, respectively). No significant difference in recurrence rates existed between the overlapping and single-stent groups. Similarly, follow-up outcomes were consistent between the two groups. Overlapping stents could be an efficient method for treating ruptured PCDAs. MDPI 2023-10-25 /pmc/articles/PMC10669846/ /pubmed/38002469 http://dx.doi.org/10.3390/brainsci13111507 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Zhou, Minghui Wu, Zengbao Maalim, Ali Abdi Zeng, Ying Guo, Xiao Zhang, Zhenhua Yuan, Xiaohong Enos, Zacharia Majaliwa Shu, Kai Lei, Ting Zhu, Mingxin Overlapping Stent Treatment for Ruptured Dissecting Aneurysms in Posterior Circulation |
title | Overlapping Stent Treatment for Ruptured Dissecting Aneurysms in Posterior Circulation |
title_full | Overlapping Stent Treatment for Ruptured Dissecting Aneurysms in Posterior Circulation |
title_fullStr | Overlapping Stent Treatment for Ruptured Dissecting Aneurysms in Posterior Circulation |
title_full_unstemmed | Overlapping Stent Treatment for Ruptured Dissecting Aneurysms in Posterior Circulation |
title_short | Overlapping Stent Treatment for Ruptured Dissecting Aneurysms in Posterior Circulation |
title_sort | overlapping stent treatment for ruptured dissecting aneurysms in posterior circulation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669846/ https://www.ncbi.nlm.nih.gov/pubmed/38002469 http://dx.doi.org/10.3390/brainsci13111507 |
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