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Identification of a Novel Acid Sphingomyelinase Activity Associated with Recombinant Human Acid Ceramidase
Acid ceramidase (AC) is a lysosomal enzyme required to hydrolyze ceramide to sphingosine by the removal of the fatty acid moiety. An inherited deficiency in this activity results in two disorders, Farber Lipogranulomatosis and spinal muscular atrophy with myoclonic epilepsy, leading to the accumulat...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669851/ https://www.ncbi.nlm.nih.gov/pubmed/38002305 http://dx.doi.org/10.3390/biom13111623 |