Cargando…
Targeting Esophageal Squamous Cell Carcinoma by Combining Copper Ionophore Disulfiram and JMJD3/UTX Inhibitor GSK J4
SIMPLE SUMMARY: Targeted therapy for malignant esophageal squamous cell carcinoma (ESCC) remains a big challenge for our clinicians. In an effort to search for the vulnerability of ESCC, we applied a high-throughput drug-screening strategy and found that CuET, a copper chelation product of disulfira...
Autores principales: | Yang, Canlin, Li, Fei, Ren, Yuanyuan, Zhang, Qianqian, Jiao, Bo, Zhang, Jianming, Huang, Junxing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670038/ https://www.ncbi.nlm.nih.gov/pubmed/38001607 http://dx.doi.org/10.3390/cancers15225347 |
Ejemplares similares
-
Inhibitor of H3K27 demethylase JMJD3/UTX GSK-J4 is a potential therapeutic option for castration resistant prostate cancer
por: Morozov, Viacheslav M., et al.
Publicado: (2017) -
JMJD3 and UTX determine fidelity and lineage specification of human neural progenitor cells
por: Shan, Yongli, et al.
Publicado: (2020) -
Histone demethylases UTX and JMJD3 are required for NKT cell development in mice
por: Northrup, Daniel, et al.
Publicado: (2017) -
The Memory of Environmental Chemical Exposure in C. elegans Is Dependent on the Jumonji Demethylases jmjd-2 and jmjd-3/utx-1
por: Camacho, Jessica, et al.
Publicado: (2018) -
The Prognostic Significance of Histone Demethylase UTX in Esophageal Squamous Cell Carcinoma
por: Li, Shau-Hsuan, et al.
Publicado: (2018)