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Targeting Esophageal Squamous Cell Carcinoma by Combining Copper Ionophore Disulfiram and JMJD3/UTX Inhibitor GSK J4

SIMPLE SUMMARY: Targeted therapy for malignant esophageal squamous cell carcinoma (ESCC) remains a big challenge for our clinicians. In an effort to search for the vulnerability of ESCC, we applied a high-throughput drug-screening strategy and found that CuET, a copper chelation product of disulfira...

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Detalles Bibliográficos
Autores principales: Yang, Canlin, Li, Fei, Ren, Yuanyuan, Zhang, Qianqian, Jiao, Bo, Zhang, Jianming, Huang, Junxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670038/
https://www.ncbi.nlm.nih.gov/pubmed/38001607
http://dx.doi.org/10.3390/cancers15225347

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