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The Interconnection between Hepatic Insulin Resistance and Metabolic Dysfunction-Associated Steatotic Liver Disease—The Transition from an Adipocentric to Liver-Centric Approach

The central mechanism involved in the pathogenesis of MAFLD is insulin resistance with hyperinsulinemia, which stimulates triglyceride synthesis and accumulation in the liver. On the other side, triglyceride and free fatty acid accumulation in hepatocytes promotes insulin resistance via oxidative st...

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Detalles Bibliográficos
Autores principales:	Vesković, Milena, Šutulović, Nikola, Hrnčić, Dragan, Stanojlović, Olivera, Macut, Djuro, Mladenović, Dušan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670061/ https://www.ncbi.nlm.nih.gov/pubmed/37998747 http://dx.doi.org/10.3390/cimb45110570

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