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Molecular Linkage between Immune System Disorders and Atherosclerosis
A strong relationship exists between immune dysfunction and cardiovascular disease. Immune dysregulation can promote the development of cardiovascular diseases as well as exacerbate their course. The disorders may occur due to the presence of primary immune defects (currently known as inborn errors...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670175/ https://www.ncbi.nlm.nih.gov/pubmed/37998729 http://dx.doi.org/10.3390/cimb45110552 |
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author | Napiórkowska-Baran, Katarzyna Schmidt, Oskar Szymczak, Bartłomiej Lubański, Jakub Doligalska, Agata Bartuzi, Zbigniew |
author_facet | Napiórkowska-Baran, Katarzyna Schmidt, Oskar Szymczak, Bartłomiej Lubański, Jakub Doligalska, Agata Bartuzi, Zbigniew |
author_sort | Napiórkowska-Baran, Katarzyna |
collection | PubMed |
description | A strong relationship exists between immune dysfunction and cardiovascular disease. Immune dysregulation can promote the development of cardiovascular diseases as well as exacerbate their course. The disorders may occur due to the presence of primary immune defects (currently known as inborn errors of immunity) and the more common secondary immune deficiencies. Secondary immune deficiencies can be caused by certain chronic conditions (such as diabetes, chronic kidney disease, obesity, autoimmune diseases, or cancer), nutritional deficiencies (including both lack of nutrients and bioactive non-nutrient compounds), and medical treatments and addictive substances. This article unravels the molecular linkage between the aforementioned immune system disorders and atherosclerosis. |
format | Online Article Text |
id | pubmed-10670175 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-106701752023-11-01 Molecular Linkage between Immune System Disorders and Atherosclerosis Napiórkowska-Baran, Katarzyna Schmidt, Oskar Szymczak, Bartłomiej Lubański, Jakub Doligalska, Agata Bartuzi, Zbigniew Curr Issues Mol Biol Review A strong relationship exists between immune dysfunction and cardiovascular disease. Immune dysregulation can promote the development of cardiovascular diseases as well as exacerbate their course. The disorders may occur due to the presence of primary immune defects (currently known as inborn errors of immunity) and the more common secondary immune deficiencies. Secondary immune deficiencies can be caused by certain chronic conditions (such as diabetes, chronic kidney disease, obesity, autoimmune diseases, or cancer), nutritional deficiencies (including both lack of nutrients and bioactive non-nutrient compounds), and medical treatments and addictive substances. This article unravels the molecular linkage between the aforementioned immune system disorders and atherosclerosis. MDPI 2023-11-01 /pmc/articles/PMC10670175/ /pubmed/37998729 http://dx.doi.org/10.3390/cimb45110552 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Napiórkowska-Baran, Katarzyna Schmidt, Oskar Szymczak, Bartłomiej Lubański, Jakub Doligalska, Agata Bartuzi, Zbigniew Molecular Linkage between Immune System Disorders and Atherosclerosis |
title | Molecular Linkage between Immune System Disorders and Atherosclerosis |
title_full | Molecular Linkage between Immune System Disorders and Atherosclerosis |
title_fullStr | Molecular Linkage between Immune System Disorders and Atherosclerosis |
title_full_unstemmed | Molecular Linkage between Immune System Disorders and Atherosclerosis |
title_short | Molecular Linkage between Immune System Disorders and Atherosclerosis |
title_sort | molecular linkage between immune system disorders and atherosclerosis |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670175/ https://www.ncbi.nlm.nih.gov/pubmed/37998729 http://dx.doi.org/10.3390/cimb45110552 |
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