High-Level Production of scFv-Fc Antibody Using an Artificial Promoter System with Transcriptional Positive Feedback Loop of Transactivator in CHO Cells

With the increasing demand for therapeutic antibodies, CHO cells have become the de facto standard as producer host cells for biopharmaceutical production. High production yields are required for antibody production, and developing a high-titer production system is increasingly crucial. This study w...

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Detalles Bibliográficos
Autores principales: Ying, Binbin, Kawabe, Yoshinori, Zheng, Feiyang, Amamoto, Yuki, Kamihira, Masamichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670205/
https://www.ncbi.nlm.nih.gov/pubmed/37998372
http://dx.doi.org/10.3390/cells12222638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670205/
https://www.ncbi.nlm.nih.gov/pubmed/37998372
http://dx.doi.org/10.3390/cells12222638

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