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Ring Chromosomes in Hematological Malignancies Are Associated with TP53 Gene Mutations and Characteristic Copy Number Variants

SIMPLE SUMMARY: Ring chromosomes (RCs) are formed when chromosome ends fuse to form a circular structure. RCs are seen in <10% of patients with blood cancers (i.e., leukemias, lymphomas, and myelomas), and are associated with poor disease outcomes. We sought to evaluate how frequently RCs arise i...

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Detalles Bibliográficos
Autores principales:	Boyd, Rachel J., Murry, Jaclyn B., Morsberger, Laura A., Klausner, Melanie, Chen, Suping, Gocke, Christopher D., McCallion, Andrew S., Zou, Ying S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670249/ https://www.ncbi.nlm.nih.gov/pubmed/38001699 http://dx.doi.org/10.3390/cancers15225439

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