Krüppel-like Factor 5 Plays an Important Role in the Pathogenesis of Chronic Pancreatitis

SIMPLE SUMMARY: This report shows that KLF5 plays a crucial role in the progression of chronic pancreatitis to pre-neoplastic precursor lesions. Notably, the deletion of Klf5 from pancreatic acinar cells by itself or in the context of activating KRAS mutation resulted in a significant reduction in i...

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Detalles Bibliográficos
Autores principales: Alavi, Maryam, Mejia-Bautista, Ana, Tang, Meiyi, Bandovic, Jela, Rosenberg, Avi Z., Bialkowska, Agnieszka B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670257/
https://www.ncbi.nlm.nih.gov/pubmed/38001687
http://dx.doi.org/10.3390/cancers15225427

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