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Mineralocorticoid Receptor Antagonism Prevents Type 2 Familial Partial Lipodystrophy Brown Adipocyte Dysfunction

Type-2 Familial Partial Lipodystrophy (FPLD2), a rare lipodystrophy caused by LMNA mutations, is characterized by a loss of subcutaneous fat from the trunk and limbs and excess accumulation of adipose tissue in the neck and face. Several studies have reported that the mineralocorticoid receptor (MR)...

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Detalles Bibliográficos
Autores principales:	Schena, Elisa, Mattioli, Elisabetta, Peres, Chiara, Zanotti, Laura, Morselli, Paolo, Iozzo, Patricia, Guzzardi, Maria Angela, Bernardini, Chiara, Forni, Monica, Nesci, Salvatore, Caprio, Massimiliano, Cecchetti, Carolina, Pagotto, Uberto, Gabusi, Elena, Cattini, Luca, Lisignoli, Gina, Blalock, William, Gambineri, Alessandra, Lattanzi, Giovanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670260/ https://www.ncbi.nlm.nih.gov/pubmed/37998321 http://dx.doi.org/10.3390/cells12222586

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